重度哮喘的流行病学与肺生理学

Epidemiology and Pulmonary Physiology of Severe Asthma.

作者信息

O'Toole Jacqueline, Mikulic Lucas, Kaminsky David A

机构信息

Department of Medicine, University of Vermont Medical Center, 111 Colchester Avenue, Burlington, VT 05401, USA.

Division of Pulmonary and Critical Care Medicine, University of Vermont Medical Center, Given D208, 89 Beaumont Avenue, Burlington, VT 05405, USA.

出版信息

Immunol Allergy Clin North Am. 2016 Aug;36(3):425-38. doi: 10.1016/j.iac.2016.03.001. Epub 2016 Jun 2.

DOI:10.1016/j.iac.2016.03.001

PMID:27401616

Abstract

The epidemiology and physiology of severe asthma are inherently linked because of varying phenotypes and expressions of asthma throughout the population. To understand how to better treat severe asthma, we must use both population data and physiologic principles to individualize therapies among groups with similar expressions of this disease.

摘要

由于哮喘在整个人口中存在不同的表型和表现形式，重度哮喘的流行病学和生理学有着内在的联系。为了了解如何更好地治疗重度哮喘，我们必须运用人群数据和生理学原理，在患有这种疾病且表现相似的群体中实现个体化治疗。