Qureshi Adnan I, Miran Muhammad Shah, Li Shijing, Jiang Meijing
Zeenat Qureshi Stroke Institute, Ping An Hospital, Shijiazhuang, China.
J Vasc Interv Neurol. 2016 Jun;9(1):60-5.
Data from electroencephalography (EEG) in preterm infants and neonates suggest that electroencephalographic abnormalities are likely present during antepartum period or fetal stage. We describe our initial effort to record fetal EEG with emphasis on technical aspects since such technique has not been developed as a viable and reproducible method.
The fetal heads were located in two pregnant volunteers (29 years old and 26 years old) with 28 weeks of gestation by ultrasound imaging. Four surface electrodes were placed on maternal abdominal surface approximately 5 cm anterior to the lateral aspect of fetal head as confirmed by acoustic shadowing of the electrodes on ultrasound. A second set of recordings were performed in first volunteer with four electrodes placed on the maternal abdominal surface in front of the uterus distant to fetal head.
The analysis in the first volunteer demonstrated that the activity consisted of mixture of theta (4-7 Hz) and delta (1-4 Hz) waves which formed approximately 70% and 30% of the background rhythm. The analysis in the second volunteer demonstrated that the activity consisted of mixture of theta and delta, which formed approximately 30% and 70% of the background rhythm. There was superimposed beta (13-30 Hz) and infrequently gamma (30-100 Hz) activity. Maternal electrocardiographic QRS complex and respiratory artifacts were seen in some leads. During second recording, the electrodes distant to fetal head recorded predominantly delta with lesser proportion of theta waves.
We report our initial experience in acquisition of fetal EEG. The findings reported here will help to guide further research into developing methodologies for the performance of fetal EEG.
来自早产儿和新生儿脑电图（EEG）的数据表明，产前或胎儿期可能存在脑电图异常。我们描述了我们记录胎儿脑电图的初步努力，重点是技术方面，因为这种技术尚未发展成为一种可行且可重复的方法。
通过超声成像确定两名怀孕志愿者（分别为29岁和26岁，孕周28周）的胎儿头部位置。在超声显示电极声影的情况下，将四个表面电极放置在母体腹部表面，位于胎儿头部侧面约5厘米前方。在第一名志愿者身上进行了第二次记录，将四个电极放置在子宫前方远离胎儿头部的母体腹部表面。
对第一名志愿者的分析表明，活动由θ波（4 - 7赫兹）和δ波（1 - 4赫兹）混合组成，分别约占背景节律的70%和30%。对第二名志愿者的分析表明，活动也由θ波和δ波混合组成，分别约占背景节律的30%和70%。有叠加的β波（13 - 30赫兹），γ波（30 - 100赫兹）活动较少见。在某些导联中可见母体心电图QRS波群和呼吸伪迹。在第二次记录期间，远离胎儿头部的电极主要记录到δ波，θ波比例较小。
我们报告了我们获取胎儿脑电图的初步经验。这里报告的结果将有助于指导进一步研究开发胎儿脑电图检查方法。
