Sandoval Karamian Amanda G, Wusthoff Courtney J
Division of Neurology, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
Division of Child Neurology, Lucile Packard Children's Hospital at Stanford, Palo Alto, CA, United States.
Front Pediatr. 2021 Nov 3;9:768670. doi: 10.3389/fped.2021.768670. eCollection 2021.
Continuous EEG (cEEG) is a fundamental neurodiagnostic tool in the care of critically ill neonates and is increasingly recommended. cEEG enhances prognostication assessment of the background brain activity, plays a role in predicting which neonates are at risk for seizures when combined with clinical factors, and allows for accurate diagnosis and management of neonatal seizures. Continuous EEG is the gold standard method for diagnosis of neonatal seizures and should be used for detection of seizures in high-risk clinical conditions, differential diagnosis of paroxysmal events, and assessment of response to treatment. High costs associated with cEEG are a limiting factor in its widespread implementation. Centralized remote cEEG interpretation, automated seizure detection, and pre-natal EEG are potential future applications of this neurodiagnostic tool.
连续脑电图(cEEG)是危重新生儿护理中的一项基本神经诊断工具,且越来越受到推荐。cEEG可增强对背景脑活动的预后评估,在结合临床因素时对预测哪些新生儿有癫痫发作风险发挥作用,并能实现新生儿癫痫的准确诊断和管理。连续脑电图是诊断新生儿癫痫的金标准方法,应用于高危临床状况下癫痫发作的检测、阵发性事件的鉴别诊断以及治疗反应评估。与cEEG相关的高成本是其广泛应用的一个限制因素。集中式远程cEEG解读、自动癫痫发作检测以及产前脑电图是这种神经诊断工具未来可能的应用方向。