McCubbin James A, Zinzow Heidi M, Hibdon Melissa A, Nathan Aaron W, Morrison Anastasia V, Hayden Gregg W, Lindberg Caitlyn, Switzer Fred S
Clemson University, Clemson, SC 29634, USA; University of South Carolina School of Medicine, Greenville, SC 29605, USA.
Clemson University, Clemson, SC 29634, USA.
Cardiovasc Psychiatry Neurol. 2016;2016:4720941. doi: 10.1155/2016/4720941. Epub 2016 Jun 15.
The purpose of this study was to examine the relationships among subclinical PTSD symptoms, blood pressure, and several variables linked to both frank PTSD and the basic psychobiological adaptation to stress. The authors recruited a sample of 91 healthy, young men and women between 18 and 35 years. We examined links among subclinical posttraumatic stress disorder symptoms, blood pressure, sleep quality, and hostility. Posttraumatic stress disorder symptoms were associated with poorer sleep quality and higher hostility scores in both women and men. In men, PTSD symptoms were also associated with elevated resting diastolic blood pressure, and sex was an important moderator of that relationship. Moreover, sleep quality and hostility are substantive mediators of the relationship between diastolic blood pressure and PTSD. Behavioral interventions designed to increase sleep quality and restructure hostile attitudes could potentially serve as preventive interventions for PTSD and the underlying cardiovascular comorbidities in young adults.
本研究的目的是检验亚临床创伤后应激障碍（PTSD）症状、血压以及与明显PTSD和应激的基本心理生物学适应相关的几个变量之间的关系。作者招募了91名年龄在18至35岁之间的健康年轻男女样本。我们研究了亚临床创伤后应激障碍症状、血压、睡眠质量和敌意之间的联系。创伤后应激障碍症状与女性和男性较差的睡眠质量以及较高的敌意得分相关。在男性中，PTSD症状还与静息舒张压升高有关，性别是该关系的重要调节因素。此外，睡眠质量和敌意是舒张压与PTSD之间关系的重要中介因素。旨在提高睡眠质量和重塑敌意态度的行为干预措施可能会成为预防年轻人PTSD及其潜在心血管合并症的干预手段。
