Krog Maria C, Nielsen Henriette Svarre, Christiansen Ole B, Kolte Astrid M
*The RPL Unit, Fertility Clinic, Copenhagen University Hospital, Copenhagen, Denmark †Department of Obstetrics and Gynaecology, Aalborg University Hospital, Aalborg, Denmark.
Clin Obstet Gynecol. 2016 Sep;59(3):474-86. doi: 10.1097/GRF.0000000000000225.
Endocrine disruptions may be important in patients experiencing recurrent pregnancy loss (RPL). This review focuses on data available on RPL and the endocrine system to investigate relevant, and perhaps modifiable, endocrine factors of importance for the disorder. Evidence indicates that some hormones may be important as immune modulators and a better understanding of this interplay has potential for improving pregnancy outcome in RPL. To date there is a lack of consensus on the effect of endocrine treatment options in RPL and there is a strong need for large randomized-controlled trials.
内分泌紊乱在复发性流产（RPL）患者中可能很重要。本综述聚焦于复发性流产与内分泌系统的现有数据，以研究该病症相关的、或许可改变的重要内分泌因素。有证据表明，某些激素作为免疫调节剂可能很重要，更好地理解这种相互作用有改善复发性流产妊娠结局的潜力。迄今为止，对于复发性流产内分泌治疗方案的效果尚无共识，迫切需要大型随机对照试验。
