Nguyen Christine T, Tsai Tina I, He Zheng, Vingrys Algis J, Lee Pei Y, Bui Bang V
Department of Optometry and Vision Sciences, University of Melbourne.
Department of Optometry and Vision Sciences, University of Melbourne;
J Vis Exp. 2016 Jul 1(113):54158. doi: 10.3791/54158.
The electroretinogram (ERG) and visual evoked potential (VEP) are commonly used to assess the integrity of the visual pathway. The ERG measures the electrical responses of the retina to light stimulation, while the VEP measures the corresponding functional integrity of the visual pathways from the retina to the primary visual cortex following the same light event. The ERG waveform can be broken down into components that reflect responses from different retinal neuronal and glial cell classes. The early components of the VEP waveform represent the integrity of the optic nerve and higher cortical centers. These recordings can be conducted in isolation or together, depending on the application. The methodology described in this paper allows simultaneous assessment of retinal and cortical visual evoked electrophysiology from both eyes and both hemispheres. This is a useful way to more comprehensively assess retinal function and the upstream effects that changes in retinal function can have on visual evoked cortical function.
视网膜电图（ERG）和视觉诱发电位（VEP）通常用于评估视觉通路的完整性。ERG测量视网膜对光刺激的电反应，而VEP测量在相同光刺激事件后从视网膜到初级视觉皮层的视觉通路的相应功能完整性。ERG波形可分解为反映不同视网膜神经元和神经胶质细胞类反应的成分。VEP波形的早期成分代表视神经和更高皮层中枢的完整性。这些记录可以单独进行，也可以一起进行，具体取决于应用情况。本文所述方法允许同时评估双眼和双侧半球的视网膜和皮层视觉诱发电生理。这是一种更全面评估视网膜功能以及视网膜功能变化对视觉诱发皮层功能可能产生的上游影响的有用方法。
