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[儿童呼吸健康与大气污染。II. 通气功能]

[Respiratory health of children and atmospheric pollution. II. Ventilatory function].

作者信息

Teculescu D, Pham Q T, Aubry C, Chau N, Viaggi M N, Henquel J C, Manciaux M

机构信息

INSERM, Unité 115, Vandoeuvre-lès-Nancy.

出版信息

Rev Mal Respir. 1989;6(3):221-8.

PMID:2740586
Abstract

Respiratory function (forced vital capacity-FVC; forced expired volume in one second-FEV1; maximal mid-expiratory flow-DEMM; peak flow-DP; maximal expiratory flow at 75-50-25% of vital capacity CV-DEMx) was studied in children of comparable age, sex and height (9 to 12 years) in a polluted zone (the exposed group n = 223) and a neighboring non-polluted zone (the control group n = 211) in the north of Lorraine. There was no significant difference in ventilatory function between the two groups. Amongst other factors capable of influencing the ventilatory function in the children we found an influence of parental smoking habits (particularly the mothers) identifiable in the non-exposed zone, above all in boys. A sub-segment analysis identified that in the absence of parental smoking, there was a negative influence of open coal fires. The discordance between the results of the measures of respiratory function and the prevalence of different respiratory symptoms, of acute infections and absenteeism from school, is probably explained by the interference of other factors which were not controlled in this study (e.g., ethnic factors and physical activity) and by the moderate level of the pollution; an over-reporting of respiratory symptoms by parents in the exposed zone could not be excluded.

摘要

对洛林北部一个污染区(暴露组,n = 223)和邻近非污染区(对照组,n = 211)中年龄、性别和身高相近(9至12岁)的儿童进行了呼吸功能研究(用力肺活量-FVC;一秒用力呼气量-FEV1;最大呼气中期流速-DEMM;峰值流速-DP;肺活量75%-50%-25%时的最大呼气流量-CV-DEMx)。两组的通气功能无显著差异。在能够影响儿童通气功能的其他因素中,我们发现在非暴露区,父母的吸烟习惯(尤其是母亲的)有影响,在男孩中尤为明显。亚组分析表明,在没有父母吸烟的情况下,开放式燃煤有负面影响。呼吸功能测量结果与不同呼吸道症状的患病率、急性感染率和缺课率之间的不一致,可能是由于本研究中未控制的其他因素(如种族因素和体育活动)的干扰以及污染程度中等所致;不能排除暴露区父母对呼吸道症状的过度报告。

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