Gadoth N, Costeff H, Harel S, Lavie P
Department of Neurology, Beilinson Medical Center, Petah Tiqva, Israel.
Sleep. 1989 Jun;12(3):233-8. doi: 10.1093/sleep/12.3.233.
The structure of sleep and number of body movements (BMS) and periodic leg movements during sleep (PMS), were studied in three unrelated girls suffering from L-DOPA responsive hereditary dystonia with marked diurnal fluctuation and in their 11 healthy, close relatives. All three girls had an increased number of BMS during rapid eye movement (REM) sleep. Five of the six parents and three siblings had abnormal PMS. One pair of parents had BMS similar to those of their affected daughter. The occurrence of BMS and PMS in the families studied may indicate a common mechanism for both. Because familial PMS is quite rare in its pure form, and this type of dystonia is also rarely encountered, the occurrence of BMS and PMS in members of these families may imply a causative relation between these two sleep-related motor phenomena.
对三名患有左旋多巴反应性遗传性肌张力障碍且有明显昼夜波动的无血缘关系女孩及其11名健康的近亲，研究了睡眠结构、身体运动次数（BMS）和睡眠期周期性腿部运动（PMS）。所有三名女孩在快速眼动（REM）睡眠期间的BMS次数均增加。六名父母中的五名和三名兄弟姐妹有异常的PMS。一对父母的BMS与他们患病女儿的相似。在所研究的家庭中BMS和PMS的出现可能表明两者存在共同机制。由于家族性PMS以其纯粹形式相当罕见，且这种类型的肌张力障碍也很少见，这些家庭成员中BMS和PMS的出现可能意味着这两种与睡眠相关的运动现象之间存在因果关系。
