百特CS 3000 plus和海莫泰克MCS plus制备单供者血小板（SDP）的研究。
Study of Single Donor Platelet (SDP) Preparation by Baxter CS 3000 plus and Haemonetics MCS plus.
作者信息
Swarup D, Dhot P S, Arora S
机构信息
CO, 302 Fd Hosp, C/o 99 APO.
Dy Comdt, CH (CC), Lucknow.
出版信息
Med J Armed Forces India. 2009 Apr;65(2):137-40. doi: 10.1016/S0377-1237(09)80127-5. Epub 2011 Jul 21.
BACKGROUND
In plateletpheresis blood is withdrawn from a donor in anticoagulant solution and separated into components. Platelets are retained and the remaining components are returned to the individual.
METHODS
The present study was aimed to compare the platelet yield and collection efficiency of Baxter CS 3000 plus and Haemonetics MCS plus cell separators and to study adverse donor reactions. Donors were selected as per the set criteria for single donor platelet (SDP) preparation. Donors' samples for pre donation and post donation platelet count were collected in EDTA and for product counts in the sample pouch attached with apheresis kits. The results were obtained by haematology analyzer. Platelet yield and collection efficiency were calculated.
RESULT
Results were tabulated for both the cell separators and analyzed. Platelet yield was marginally better with Baxter CS 3000 plus but collection efficiency was better with the Haemonetics MCS plus. Residual white cells were more in single donor platelet concentrate preparation by MCS plus. Adverse donor reactions were similar with both cell separators, in form of mild citrate toxicity and mild to moderate pain at phlebotomy site.
CONCLUSION
Findings of the present study along with other factors such as less priming time for kit, portability of cell separator, better patient comfort owing to single arm venous access and lesser cost suggest that Haemonetics MCS plus is a better choice as compared to Baxter CS 3000 plus cell separator.
背景
在血小板单采术中，将抗凝溶液中的供体血液抽出并分离成各种成分。保留血小板，其余成分回输给个体。
方法
本研究旨在比较百特CS 3000 plus和血液技术公司MCS plus血细胞分离机的血小板产量和采集效率，并研究供体的不良反应。根据单采血小板（SDP）制备的既定标准选择供体。在乙二胺四乙酸（EDTA）中采集供体献血前和献血后的血小板计数样本，在与单采套件相连的样本袋中采集产品计数样本。通过血液分析仪获得结果。计算血小板产量和采集效率。
结果
将两种血细胞分离机的结果制成表格并进行分析。百特CS 3000 plus的血小板产量略高，但血液技术公司MCS plus的采集效率更高。MCS plus制备的单采血小板浓缩物中的残留白细胞更多。两种血细胞分离机引起的供体不良反应相似，表现为轻度枸橼酸盐毒性和静脉穿刺部位轻度至中度疼痛。
结论
本研究结果以及其他因素，如套件预充时间短、血细胞分离机便携性、单臂静脉通路使患者舒适度更高以及成本更低，表明与百特CS 3000 plus血细胞分离机相比，血液技术公司MCS plus是更好的选择。
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