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[秘鲁利马吉列尔莫·阿尔梅纳拉国立医院外科手术中社区获得性和医院内腹腔内感染的微生物学及耐药情况]

[Microbiological and resistance profiles of community acquired and nosocomial intra abdominal infections in surgery of National Hospital Guillermo Almenara, Lima, Peru].

作者信息

Revoredo Rego Fernando, Huamán Egoávil Eduardo, Zegarra Cavani Sergio, Auris Mora Hugo, Valderrama Barrientos Roberto

机构信息

Servicio de Cirugía de Páncreas, Bazo y Retroperitoneo, Departamento De Cirugía General, Hospital Nacional Guillermo Almenara Irigoyen. Lima, Perú.

Servicio de Cirugía de Emergencia y Cuidados Críticos Quirúrgicos, Departamento de Cirugía General, Hospital Nacional Guillermo Almenara Irigoyen. Lima, Perú.

出版信息

Rev Gastroenterol Peru. 2016 Apr-Jun;36(2):115-22.

Abstract

OBJECTIVE

To determine the microbiological and resistance profiles of community acquired and nosocomial intra abdominal infections (IAIs) at the Surgery Service of Emergency and surgery critical care units from the Hospital Nacional Guillermo Almenara Irigoyen.

MATERIAL AND METHODS

From August 1st, 2013 till July 31st, 2014, patients undergoing surgery/interventional drainage for IAIs were included.

RESULTS

The suitable cultures for the analysis were 169 (74 bile and 95 no bile cultures; 142 community acquired and 27 nosocomials). The microorganims more frequently isolated were E. coli (63.3%), K. pneumoniae (12%) and Enterococcus spp. (10%). The 43.5% of E. coli and the 21.23% of Klebsiella were ESBL producers. The carbapenems were the most active agents in vitro (100%), while the quinolones showed high resistance (>50%).

CONCLUSIONS

E. coli was the most common microorganism in the IAIs. Because of the quinolone’s high “in vitro” resistance, they should not be recommended as initial empirical therapy.

摘要

目的

确定国立吉列尔莫·阿尔梅纳拉·伊里戈延医院急诊外科和外科重症监护病房社区获得性和医院内腹腔内感染(IAIs)的微生物学和耐药情况。

材料与方法

纳入2013年8月1日至2014年7月31日期间因IAIs接受手术/介入引流的患者。

结果

适合分析的培养物有169份(74份胆汁培养物和95份非胆汁培养物;142份社区获得性培养物和27份医院内感染培养物)。最常分离出的微生物是大肠杆菌(63.3%)、肺炎克雷伯菌(12%)和肠球菌属(10%)。43.5%的大肠杆菌和21.23%的克雷伯菌产超广谱β-内酰胺酶(ESBL)。碳青霉烯类在体外是最有效的药物(100%),而喹诺酮类显示出高耐药性(>50%)。

结论

大肠杆菌是IAIs中最常见的微生物。由于喹诺酮类在“体外”具有高耐药性,不建议将其作为初始经验性治疗药物。

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