Gunasekaran Prasad, Panaich Sidakpal, Briasoulis Alexandros, Cardozo Shaun, Afonso Luis
Division of Cardiology, Wayne State University, Detroit Medical Center, 3990 John R, 8-Brush, Harper University Hospital, Detroit, Michigan-48201. United States.
Curr Cardiol Rev. 2017;13(1):32-40. doi: 10.2174/1573403x12666160712095938.
Subclinical left ventricular (LV) dysfunction refers to subtle abnormalities in LV function which typically precede a reduction in the left ventricular ejection fraction (LVEF). The assessment of myocardial function using LVEF, a radial metric of systolic function, is subject to load dependence, intra-observer and inter-observer variability. Reductions in LVEF typically manifest late in the disease process thus compromising the ability to intervene before irreversible impairment of systolic performance sets in. 2-Dimensional speckle tracking echocardiography (2D-STE), a novel strain imaging modality has shown promise as a sensitive indicator of myocardial contractility. It arms the clinician with a powerful and practical tool to rapidly quantify cardiac mechanics, circumventing several inherent limitations of conventional echocardiography. This article highlights the incremental utility of 2D-STE in the detection of subclinical LV dysfunction.
亚临床左心室（LV）功能障碍是指左心室功能的细微异常，通常先于左心室射血分数（LVEF）降低出现。使用LVEF（一种收缩功能的径向指标）评估心肌功能会受到负荷依赖性、观察者内和观察者间变异性的影响。LVEF降低通常在疾病过程后期才表现出来，从而削弱了在收缩功能出现不可逆损害之前进行干预的能力。二维斑点追踪超声心动图（2D-STE）是一种新型应变成像模式，已显示出作为心肌收缩力敏感指标的前景。它为临床医生提供了一种强大而实用的工具，可快速量化心脏力学，规避了传统超声心动图的几个固有局限性。本文重点介绍了2D-STE在检测亚临床LV功能障碍方面的增量效用。
