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Differences in prognosis of stereotyped IGHV3-21 chronic lymphocytic leukaemia according to additional molecular and cytogenetic aberrations.

作者信息

Jeromin S, Haferlach C, Dicker F, Alpermann T, Haferlach T, Kern W

机构信息

MLL Munich Leukemia Laboratory, Munich, Germany.

出版信息

Leukemia. 2016 Nov;30(11):2251-2253. doi: 10.1038/leu.2016.189. Epub 2016 Jul 14.

DOI:10.1038/leu.2016.189
PMID:27411488
Abstract
摘要

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1
Clinical effect of stereotyped B-cell receptor immunoglobulins in chronic lymphocytic leukaemia: a retrospective multicentre study.定型B细胞受体免疫球蛋白在慢性淋巴细胞白血病中的临床疗效:一项回顾性多中心研究
Lancet Haematol. 2014 Nov;1(2):e74-84. doi: 10.1016/S2352-3026(14)00005-2. Epub 2014 Nov 3.
2
ARResT/AssignSubsets: a novel application for robust subclassification of chronic lymphocytic leukemia based on B cell receptor IG stereotypy.ARResT/AssignSubsets:一种基于 B 细胞受体 IG 重排的慢性淋巴细胞白血病稳健亚分类的新应用。
Bioinformatics. 2015 Dec 1;31(23):3844-6. doi: 10.1093/bioinformatics/btv456. Epub 2015 Aug 6.
3
Immunoglobulin genes in chronic lymphocytic leukemia: key to understanding the disease and improving risk stratification.
慢性淋巴细胞白血病中的免疫球蛋白基因:理解该疾病及改善风险分层的关键
Haematologica. 2017 Jun;102(6):968-971. doi: 10.3324/haematol.2017.165605.
Not all IGHV3-21 chronic lymphocytic leukemias are equal: prognostic considerations.
并非所有IGHV3 - 21慢性淋巴细胞白血病都相同:预后考量
Blood. 2015 Jan 29;125(5):856-9. doi: 10.1182/blood-2014-09-600874. Epub 2014 Dec 17.
4
Association between molecular lesions and specific B-cell receptor subsets in chronic lymphocytic leukemia.慢性淋巴细胞白血病中分子病变与特异性 B 细胞受体亚群的关系。
Blood. 2013 Jun 13;121(24):4902-5. doi: 10.1182/blood-2013-02-486209. Epub 2013 May 1.
5
Distinct patterns of novel gene mutations in poor-prognostic stereotyped subsets of chronic lymphocytic leukemia: the case of SF3B1 and subset #2.慢性淋巴细胞白血病预后不良定型亚群中新基因突变的独特模式:SF3B1 和亚型 2 的情况。
Leukemia. 2013 Nov;27(11):2196-9. doi: 10.1038/leu.2013.98. Epub 2013 Apr 5.
6
Stereotyped B-cell receptors in one-third of chronic lymphocytic leukemia: a molecular classification with implications for targeted therapies.三分之一的慢性淋巴细胞白血病存在定型 B 细胞受体:一种具有靶向治疗意义的分子分类。
Blood. 2012 May 10;119(19):4467-75. doi: 10.1182/blood-2011-11-393694. Epub 2012 Mar 13.
7
Prognostic factors identified three risk groups in the LRF CLL4 trial, independent of treatment allocation.LRF CLL4 试验确定了预后因素,将患者分为三个风险组,与治疗分配无关。
Haematologica. 2010 Oct;95(10):1705-12. doi: 10.3324/haematol.2010.025338. Epub 2010 May 29.
8
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Haematologica. 2010 Sep;95(9):1519-25. doi: 10.3324/haematol.2009.021014. Epub 2010 Apr 26.
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Correlation of flow cytometrically determined expression of ZAP-70 using the SBZAP antibody with IgVH mutation status and cytogenetics in 1,229 patients with chronic lymphocytic leukemia.使用SBZAP抗体通过流式细胞术测定ZAP-70表达与1229例慢性淋巴细胞白血病患者的IgVH突变状态及细胞遗传学的相关性。
Cytometry B Clin Cytom. 2009 Nov;76(6):385-93. doi: 10.1002/cyto.b.20483.
10
Use of IGHV3-21 in chronic lymphocytic leukemia is associated with high-risk disease and reflects antigen-driven, post-germinal center leukemogenic selection.IGHV3-21在慢性淋巴细胞白血病中的应用与高危疾病相关,并反映了抗原驱动的生发中心后致白血病选择。
Blood. 2008 May 15;111(10):5101-8. doi: 10.1182/blood-2007-12-130229. Epub 2008 Mar 7.