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Double IGHV DNA gene rearrangements in CLL: influence of mixed-mutated and -unmutated rearrangements on outcomes in CLL.

作者信息

Heyman B, Volkheimer A D, Weinberg J B

机构信息

Duke University and Durham Veterans Affairs Medical Centers, Department of Medicine, Durham, NC, USA.

出版信息

Blood Cancer J. 2016 Jul 1;6(7):e440. doi: 10.1038/bcj.2016.49.

DOI:10.1038/bcj.2016.49
PMID:27367477
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5030375/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02e5/5030375/c9efe137f599/bcj201649f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02e5/5030375/c9efe137f599/bcj201649f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02e5/5030375/c9efe137f599/bcj201649f1.jpg

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本文引用的文献

1
Flow cytometric identification of 76 patients with biclonal disease among 5523 patients with chronic lymphocytic leukaemia (B-CLL) and its genetic characterization.流式细胞术鉴定 5523 例慢性淋巴细胞白血病（B-CLL）患者中的 76 例双克隆疾病及其遗传特征。
Br J Haematol. 2014 Feb;164(4):565-9. doi: 10.1111/bjh.12652. Epub 2013 Nov 14.
2
Double productive immunoglobulin sequence rearrangements in patients with chronic lymphocytic leukemia.慢性淋巴细胞白血病患者中的双重生产性免疫球蛋白序列重排。
Am J Hematol. 2013 Apr;88(4):277-82. doi: 10.1002/ajh.23396. Epub 2013 Feb 28.
3
Immunoglobulin sequence analysis and prognostication in CLL: guidelines from the ERIC review board for reliable interpretation of problematic cases.
IGHV mutational status testing in chronic lymphocytic leukemia.
慢性淋巴细胞白血病中的IGHV突变状态检测
Am J Hematol. 2017 Dec;92(12):1393-1397. doi: 10.1002/ajh.24808. Epub 2017 Jul 29.
4
Integrative systems medicine approaches to identify molecular targets in lymphoid malignancies.用于识别淋巴系统恶性肿瘤分子靶点的整合系统医学方法。
J Transl Med. 2016 Sep 1;14(1):252. doi: 10.1186/s12967-016-1018-2.
免疫球蛋白序列分析和 CLL 预后：ERIC 审查委员会关于可靠解读疑难病例的指南。
Leukemia. 2011 Jun;25(6):979-84. doi: 10.1038/leu.2011.49. Epub 2011 Apr 1.
4
Evidence for the significant role of immunoglobulin light chains in antigen recognition and selection in chronic lymphocytic leukemia.免疫球蛋白轻链在慢性淋巴细胞白血病抗原识别和选择中的重要作用的证据。
Blood. 2009 Jan 8;113(2):403-11. doi: 10.1182/blood-2008-07-166868. Epub 2008 Oct 23.
5
Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines.慢性淋巴细胞白血病诊断与治疗指南：慢性淋巴细胞白血病国际研讨会报告，更新美国国立癌症研究所工作组1996年指南
Blood. 2008 Jun 15;111(12):5446-56. doi: 10.1182/blood-2007-06-093906. Epub 2008 Jan 23.
6
Clinical and molecular predictors of disease severity and survival in chronic lymphocytic leukemia.慢性淋巴细胞白血病疾病严重程度和生存的临床及分子预测指标
Am J Hematol. 2007 Dec;82(12):1063-70. doi: 10.1002/ajh.20987.
7
Progressive immunoglobulin gene mutations in chronic lymphocytic leukemia: evidence for antigen-driven intraclonal diversification.慢性淋巴细胞白血病中免疫球蛋白基因的渐进性突变：抗原驱动的克隆内多样化的证据。
Blood. 2007 Feb 15;109(4):1559-67. doi: 10.1182/blood-2006-05-020644. Epub 2006 Nov 2.
8
IMGT, the international ImMunoGeneTics information system: a standardized approach for immunogenetics and immunoinformatics.国际免疫基因信息系统（IMGT）：免疫遗传学和免疫信息学的标准化方法。
Immunome Res. 2005 Sep 20;1:3. doi: 10.1186/1745-7580-1-3.
9
Chronic lymphocytic leukemia.慢性淋巴细胞白血病
N Engl J Med. 2005 Feb 24;352(8):804-15. doi: 10.1056/NEJMra041720.
10
Biallelic IgH rearrangements in patients with indolent lymphoproliferative disorders: molecular and practical implications.惰性淋巴细胞增殖性疾病患者的双等位基因免疫球蛋白重排：分子与实际意义
J Cell Physiol. 2004 May;199(2):217-26. doi: 10.1002/jcp.10459.