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Multidimensional regulation of lipoprotein lipase: impact on biochemical and cardiovascular phenotypes.

作者信息

Hegele Robert A

机构信息

Department of Medicine and Robarts Research Institute, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada

出版信息

J Lipid Res. 2016 Sep;57(9):1601-7. doi: 10.1194/jlr.C070946. Epub 2016 Jul 13.

DOI:10.1194/jlr.C070946

PMID:27412676

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5003155/

Abstract

摘要

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Multidimensional regulation of lipoprotein lipase: impact on biochemical and cardiovascular phenotypes.

J Lipid Res. 2016 Sep;57(9):1601-7. doi: 10.1194/jlr.C070946. Epub 2016 Jul 13.

Activation of lipoprotein lipase by synthetic fragments of apolipoprotein C-II.

Ann N Y Acad Sci. 1980;348:213-23. doi: 10.1111/j.1749-6632.1980.tb21302.x.

[Role and mechanism of lipoprotein lipase activity in lipoprotein metabolism].

Przegl Lek. 1987;44(4):406-9.

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Atherosclerosis. 1980 Jan;35(1):29-40. doi: 10.1016/0021-9150(80)90025-8.

Redistribution of apolipoproteins C removed from human very low density lipoprotein during in vitro lipolysis by lipoprotein lipase.

Biochimie. 1981 Jun;63(6):485-94. doi: 10.1016/s0300-9084(81)80081-8.

[Lipoprotein lipase].

Ned Tijdschr Geneeskd. 1992 Apr 11;136(15):727-30.

Apolipoprotein C-II and lipoprotein lipase activity.

Ric Clin Lab. 1982 Jan-Mar;12(1):35-40. doi: 10.1007/BF02909307.

Dynamics of C-apolipoproteins in the enzymatic interconversions of plasma lipoproteins.

Ric Clin Lab. 1982 Jan-Mar;12(1):41-9. doi: 10.1007/BF02909308.

Lipoprotein lipase: mechanism of action and role in lipoprotein metabolism.

Prog Lipid Res. 1983;22(1):35-78. doi: 10.1016/0163-7827(83)90003-6.

Lipoprotein lipase activator deficiency in very low density lipoproteins in rat nephrotic syndrome.

Experientia. 1978 Aug 15;34(8):1044-5. doi: 10.1007/BF01915337.

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Variants with large effects on blood lipids and the role of cholesterol and triglycerides in coronary disease.

Nat Genet. 2016 Jun;48(6):634-9. doi: 10.1038/ng.3561. Epub 2016 May 2.

Pathogenic classification of LPL gene variants reported to be associated with LPL deficiency.

J Clin Lipidol. 2016 Mar-Apr;10(2):394-409. doi: 10.1016/j.jacl.2015.12.015. Epub 2015 Dec 24.

The ANGPTL3-4-8 model, a molecular mechanism for triglyceride trafficking.

Open Biol. 2016 Apr;6(4):150272. doi: 10.1098/rsob.150272.

Angiopoietin-like 4 promotes intracellular degradation of lipoprotein lipase in adipocytes.

J Lipid Res. 2016 Sep;57(9):1670-83. doi: 10.1194/jlr.M067363. Epub 2016 Mar 31.

Role of lipoprotein lipase in lipid metabolism.

Curr Opin Lipidol. 2016 Jun;27(3):233-41. doi: 10.1097/MOL.0000000000000297.

Regulation of lipid metabolism by angiopoietin-like proteins.

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Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease.

N Engl J Med. 2016 Mar 24;374(12):1134-44. doi: 10.1056/NEJMoa1507652. Epub 2016 Mar 2.

Inactivating Variants in ANGPTL4 and Risk of Coronary Artery Disease.

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Increased Remnant Cholesterol Explains Part of Residual Risk of All-Cause Mortality in 5414 Patients with Ischemic Heart Disease.

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相似文献

Multidimensional regulation of lipoprotein lipase: impact on biochemical and cardiovascular phenotypes.

J Lipid Res. 2016 Sep;57(9):1601-7. doi: 10.1194/jlr.C070946. Epub 2016 Jul 13.

Activation of lipoprotein lipase by synthetic fragments of apolipoprotein C-II.

Ann N Y Acad Sci. 1980;348:213-23. doi: 10.1111/j.1749-6632.1980.tb21302.x.

[Role and mechanism of lipoprotein lipase activity in lipoprotein metabolism].

Przegl Lek. 1987;44(4):406-9.

Apolipoprotein CII and lipoprotein lipase in human nephrotic syndrome.

Atherosclerosis. 1980 Jan;35(1):29-40. doi: 10.1016/0021-9150(80)90025-8.

Redistribution of apolipoproteins C removed from human very low density lipoprotein during in vitro lipolysis by lipoprotein lipase.

Biochimie. 1981 Jun;63(6):485-94. doi: 10.1016/s0300-9084(81)80081-8.

[Lipoprotein lipase].

Ned Tijdschr Geneeskd. 1992 Apr 11;136(15):727-30.

Apolipoprotein C-II and lipoprotein lipase activity.

Ric Clin Lab. 1982 Jan-Mar;12(1):35-40. doi: 10.1007/BF02909307.

Dynamics of C-apolipoproteins in the enzymatic interconversions of plasma lipoproteins.

Ric Clin Lab. 1982 Jan-Mar;12(1):41-9. doi: 10.1007/BF02909308.

Lipoprotein lipase: mechanism of action and role in lipoprotein metabolism.

Prog Lipid Res. 1983;22(1):35-78. doi: 10.1016/0163-7827(83)90003-6.

Lipoprotein lipase activator deficiency in very low density lipoproteins in rat nephrotic syndrome.

Experientia. 1978 Aug 15;34(8):1044-5. doi: 10.1007/BF01915337.

引用本文的文献

The interplay of factors in metabolic syndrome: understanding its roots and complexity.

Mol Med. 2024 Dec 27;30(1):279. doi: 10.1186/s10020-024-01019-y.

Instrumental variable and colocalization analyses identify endotrophin and HTRA1 as potential therapeutic targets for coronary artery disease.

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Front Endocrinol (Lausanne). 2022 Dec 1;13:960343. doi: 10.3389/fendo.2022.960343. eCollection 2022.

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BMJ Case Rep. 2022 Nov 24;15(11):e251411. doi: 10.1136/bcr-2022-251411.

Mitochondrial dysfunction is associated with lipid metabolism disorder and upregulation of angiotensin-converting enzyme 2.

PLoS One. 2022 Jun 29;17(6):e0270418. doi: 10.1371/journal.pone.0270418. eCollection 2022.

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Front Physiol. 2021 Dec 23;12:787535. doi: 10.3389/fphys.2021.787535. eCollection 2021.

Combined Lipidomics and Network Pharmacology Study of Protective Effects of against Blood Stasis Syndrome.

Evid Based Complement Alternat Med. 2021 Mar 19;2021:5526778. doi: 10.1155/2021/5526778. eCollection 2021.

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Front Endocrinol (Lausanne). 2020 Jul 24;11:455. doi: 10.3389/fendo.2020.00455. eCollection 2020.

Lipids and cancer: Emerging roles in pathogenesis, diagnosis and therapeutic intervention.

Adv Drug Deliv Rev. 2020;159:245-293. doi: 10.1016/j.addr.2020.07.013. Epub 2020 Jul 23.

Clinical review on triglycerides.

Eur Heart J. 2020 Jan 1;41(1):99-109c. doi: 10.1093/eurheartj/ehz785.

本文引用的文献

ApoC-III inhibits clearance of triglyceride-rich lipoproteins through LDL family receptors.

J Clin Invest. 2016 Aug 1;126(8):2855-66. doi: 10.1172/JCI86610. Epub 2016 Jul 11.

Variants with large effects on blood lipids and the role of cholesterol and triglycerides in coronary disease.

Nat Genet. 2016 Jun;48(6):634-9. doi: 10.1038/ng.3561. Epub 2016 May 2.

Pathogenic classification of LPL gene variants reported to be associated with LPL deficiency.

J Clin Lipidol. 2016 Mar-Apr;10(2):394-409. doi: 10.1016/j.jacl.2015.12.015. Epub 2015 Dec 24.

The ANGPTL3-4-8 model, a molecular mechanism for triglyceride trafficking.

Open Biol. 2016 Apr;6(4):150272. doi: 10.1098/rsob.150272.

Angiopoietin-like 4 promotes intracellular degradation of lipoprotein lipase in adipocytes.

J Lipid Res. 2016 Sep;57(9):1670-83. doi: 10.1194/jlr.M067363. Epub 2016 Mar 31.

Role of lipoprotein lipase in lipid metabolism.

Curr Opin Lipidol. 2016 Jun;27(3):233-41. doi: 10.1097/MOL.0000000000000297.

Regulation of lipid metabolism by angiopoietin-like proteins.

Curr Opin Lipidol. 2016 Jun;27(3):249-56. doi: 10.1097/MOL.0000000000000290.

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease.

N Engl J Med. 2016 Mar 24;374(12):1134-44. doi: 10.1056/NEJMoa1507652. Epub 2016 Mar 2.

Inactivating Variants in ANGPTL4 and Risk of Coronary Artery Disease.

N Engl J Med. 2016 Mar 24;374(12):1123-33. doi: 10.1056/NEJMoa1510926. Epub 2016 Mar 2.

Increased Remnant Cholesterol Explains Part of Residual Risk of All-Cause Mortality in 5414 Patients with Ischemic Heart Disease.

Clin Chem. 2016 Apr;62(4):593-604. doi: 10.1373/clinchem.2015.253757. Epub 2016 Feb 17.

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Multidimensional regulation of lipoprotein lipase: impact on biochemical and cardiovascular phenotypes.

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