Anagnostou Katherine, Swan Kate, Fox Adam T
Department of Paediatric Allergy, Guy's and St Thomas' Hospitals NHS Foundation Trust, Westminster Bridge Road, London SE1 7EH, UK.
Children (Basel). 2015 Dec 15;2(4):439-52. doi: 10.3390/children2040439.
Many children now suffer with a food allergy, immunoglobulin E (IgE) and/or non-IgE mediated. Food allergies have a significant impact on the child's quality of life, as well as that of their family, due to the resultant dietary restrictions and the constant threat of a potentially life-threatening reaction. At present, there is no cure for food allergies, but there are exciting advances occurring in the management of IgE mediated allergies, including a more active approach to management with anticipatory screening testing, early introduction of common food allergens, active tolerance induction, use of biologics and active risk management. These areas will be discussed in this review.
现在许多儿童患有食物过敏,由免疫球蛋白E(IgE)和/或非IgE介导。由于随之而来的饮食限制以及潜在的危及生命反应的持续威胁,食物过敏对儿童及其家庭的生活质量都有重大影响。目前,食物过敏无法治愈,但在IgE介导的过敏症管理方面正取得令人兴奋的进展,包括采用更积极的管理方法,如进行预期筛查测试、尽早引入常见食物过敏原、主动诱导耐受、使用生物制剂以及积极的风险管理。本综述将对这些领域进行讨论。