Suppr超能文献

连续喉镜定量评估运动和恢复过程中的喉部行为。

Continuous laryngoscopy quantitates laryngeal behaviour in exercise and recovery.

机构信息

Dept of Pediatrics, National Jewish Health, Denver, CO, USA

Dept of Otolaryngology, University of Colorado School of Medicine, Aurora, CO, USA.

出版信息

Eur Respir J. 2016 Oct;48(4):1192-1200. doi: 10.1183/13993003.00160-2016. Epub 2016 Jul 13.

Abstract

Exercise-induced laryngeal obstruction (E-ILO) causes exertional dyspnoea. There is no standardised methodology which characterises laryngeal obstruction in relation to exercise or links laryngeal obstruction and dyspnoea severity. Continuous laryngoscopy during exercise (CLE) may improve diagnostic sensitivity by enabling laryngeal visualisation at peak work capacity in patients with rapidly resolving obstruction. The time course of laryngeal obstruction across exercise and recovery has not been quantitated until this report.Adolescents and young adults referred for CLE were laryngoscopically monitored across rest, maximal cycle ergometry exercise, and recovery. Three reviewers, blinded to time sequencing, rated inspiratory glottic and supraglottic obstruction during 10 windows of 15-s corresponding to rest, 25%, 50%, 75%, 90% and 100% of individual symptom-limited peak work capacity (expressed in Watts), and four consecutive recovery windows.85 patients were screened and 71 included. Over 96% of time windows were interpretable. Laryngeal obstruction severity reached observed maximal levels at peak work capacity, and rapidly resolved. A spectrum of observed maximal obstruction was measured.CLE provides interpretable data demonstrating laryngeal obstruction in patients with suspected E-ILO that is more severe at peak work capacity than during rest, submaximal exercise, or recovery. Observed maximal obstruction was infrequently severe and rapidly resolved.

摘要

运动诱发的喉阻塞(E-ILO)导致运动性呼吸困难。目前尚无标准化的方法学来描述与运动相关的喉阻塞,也无法将喉阻塞与呼吸困难的严重程度联系起来。在运动期间进行连续喉镜检查(CLE)可以提高诊断敏感性,使在快速缓解阻塞的患者的最大工作能力时能够对喉部进行可视化。直到本报告为止,尚未对运动和恢复过程中的喉阻塞时间过程进行定量。

本研究纳入了因 CLE 而转诊的青少年和年轻成年人,在休息、最大循环测力计运动和恢复期间对其进行喉镜监测。三位审阅者对 10 个 15 秒窗口(对应于休息、25%、50%、75%、90%和 100%的个体症状限制峰值工作能力)和 4 个连续恢复窗口期间的吸气性声门和喉上部阻塞进行了盲法、时间顺序的评分。

71 名患者符合纳入标准,85 名患者被筛选。超过 96%的时间窗口可解释。喉阻塞严重程度在达到最大工作能力时达到观察到的最高水平,并迅速缓解。观察到的最大阻塞程度呈连续谱分布。

CLE 提供了可解释的数据,证明了怀疑患有 E-ILO 的患者存在喉阻塞,其在峰值工作能力时比在休息、次最大运动或恢复期间更为严重。观察到的最大阻塞程度并不常见,且迅速缓解。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验