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良性胆管狭窄的外科治疗:64例单中心经验

Surgical treatment for benign biliary strictures: single-center experience on 64 cases.

作者信息

Cui Yunfeng, Zhang Hongtao, Cui Naiqiang, Li Zhonglian

机构信息

Department of Surgery, Tianjin Nankai Hospital, Nankai Clinical School of Medicine, Tianjin Medical University, 122 Sanwei Road Nankai District, Tianjin 300100, China.

出版信息

EXCLI J. 2012 Jul 19;11:390-8. eCollection 2012.

Abstract

OBJECTIVES

In order to describe treatment options for postoperative benign biliary strictures and find a proper approach for treatment, we describe the presentation and management of postoperative biliary stricture in 64 patients.

METHODS

Demographical and clinical data from 64 patients undergoing surgical reconstructions by retrospective methods during the past 6 years were analyzed. Clinical features of Grade I and II group versus Grade III and IV group and bile duct plasty versus biliojejunostomy were compared.

RESULTS

Of the 64 patients, 21 received bile duct plasty and the other 43 underwent biliojejunostomy. Patients with bigger bile duct dilatation had better outcomes than those with smaller one, P=0.0372. Hepaticojejunostomy was correlated to better outcomes than other surgical procedures, P=0.0483. Bile duct plasty was related to Bismuth classification Type I, P=0.0001. But biliojejunostomy was related to Bismuth classification Type II, P=0.0001 and Type III, P=0.0059. Patients with bigger bile duct dilatation had more biliojejunostomy than those with smaller one, P=0.0001.

CONCLUSION

Both biliojejunostomy and bile duct plasty had good treatment outcomes. Bile duct plasty should be confined to patients with a degree of bile duct dilatation less than 1.5 cm and Bismuth classification (Type I). The degree of dilatation, hepaticojejunostomy and postoperative morbidity were factors statistically correlated to long term outcomes.

摘要

目的

为了描述术后良性胆管狭窄的治疗选择并找到合适的治疗方法,我们描述了64例患者术后胆管狭窄的表现及处理。

方法

采用回顾性方法分析了过去6年中64例行手术重建患者的人口统计学和临床资料。比较了I级和II级组与III级和IV级组的临床特征以及胆管成形术与胆肠吻合术的情况。

结果

64例患者中,21例行胆管成形术,另外43例行胆肠吻合术。胆管扩张较大的患者比扩张较小的患者预后更好,P = 0.0372。肝肠吻合术比其他手术方法的预后更好,P = 0.0483。胆管成形术与Bismuth分类I型相关,P = 0.0001。但胆肠吻合术与Bismuth分类II型相关,P = 0.0001,与III型相关,P = 0.0059。胆管扩张较大的患者比扩张较小的患者接受胆肠吻合术的更多,P = 0.0001。

结论

胆肠吻合术和胆管成形术均有良好的治疗效果。胆管成形术应限于胆管扩张程度小于1.5 cm且为Bismuth分类(I型)的患者。扩张程度、肝肠吻合术和术后发病率是与长期预后有统计学相关性的因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac19/4942806/13c4c0b9688a/EXCLI-11-390-t-001.jpg

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