Masir N, Cheong S K, Noordin K
a Department of Histopathology Faculty of Medicine , Universiti Kebangsaan Malaysia , Jalan Yaacob Latif, Cheras, 56000 Kuala Lumpur , Malaysia.
b Department of Haematology Faculty of Medicine , Universiti Kebangsaan Malaysia , Jalan Yaacob Latif, Cheras, 56000 Kuala Lumpur , Malaysia.
Hematology. 2001;6(3):187-92. doi: 10.1080/10245332.2001.11746571.
A case of signet-ring cell lymphoma diagnosed initially by fine needle aspiration cytology is reported. This rare tumor is a variant of follicular lymphoma, which closely resembles metastatic adenocarcinoma and other tumors which exhibit signet-ring cell appearance. Correct diagnosis can be achieved by careful morphologic analysis together with positive reactivity with lymphoid markers. The cytohistologic, immunohistochemical and electron microscopic features are described, and the differ ential diagnostic considerations are discussed in the report.
报告了一例最初通过细针穿刺细胞学诊断的印戒细胞淋巴瘤病例。这种罕见的肿瘤是滤泡性淋巴瘤的一种变体，与转移性腺癌和其他呈现印戒细胞外观的肿瘤极为相似。通过仔细的形态学分析以及与淋巴标记物的阳性反应可实现正确诊断。文中描述了细胞组织学、免疫组织化学和电子显微镜特征，并在报告中讨论了鉴别诊断的相关考量因素。
