Riaño Galán I, Rey Galán C, Del Molino Anta A, Santos Rodríguez F, Malaga Guerrero S, Crespo Hernández M
Departamento de Pediatría, Hospital Materno-Infantil de la Seguridad Social, Nuestra Señora de Covadonga, Facultad de Medicina, Oviedo.
An Esp Pediatr. 1989 Apr;30(4):275-8.
Clinical characteristics, evolution of growth, and glomerular rate were analysed in 22 patients, younger than 14 years, with chronic renal failure (glomerular filtration rate: 32.6 +/- 24.8 ml/min/1.73 m2, x +/- DS) with a minimal follow-up of 6 months (3.5 +/- 3.3 years). Recurrent urinary tract infections were the most common initial clinical features (27%) and obstructive uropathies constituted the most frequent etiology (41%). Renal failure progression rate, which was assessed by means of 1 to serum creatinine concentration ratio, was faster in the group of children with glomerulonephropaties. At the diagnosis, one out of 3 children had short stature. At the end of the follow-up time, the delay of growth did not significatively modified (-1.6 +/- 2.2 DS versus -2.1 +/- 1.2 DS, p greater than 0.05).
对22名14岁以下的慢性肾衰竭患者（肾小球滤过率：32.6±24.8 ml/min/1.73 m2，x±标准差）的临床特征、生长发育情况及肾小球滤过率进行了分析，这些患者最少随访6个月（3.5±3.3年）。反复尿路感染是最常见的初始临床特征（27%），梗阻性尿路病是最常见的病因（41%）。通过血清肌酐浓度比值评估的肾衰竭进展速度，在肾小球肾炎患儿组中更快。诊断时，三分之一的儿童身材矮小。随访结束时，生长迟缓没有显著变化（-1.6±2.2标准差对-2.1±1.2标准差，p＞0.05）。
