Betancur-Sánchez A M, Vásquez-Trespalacios E M, Sardi-Correa C
Grupo de Investigación Observatorio de la Salud Pública, Universidad CES, Medellín, Colombia.
Departamento de Epidemiología, Grupo de Investigación Observatorio de la Salud Pública, Universidad CES , Medellín, Colombia.
Arch Soc Esp Oftalmol. 2017 Jan;92(1):12-18. doi: 10.1016/j.oftal.2016.05.008. Epub 2016 Jul 13.
To evaluate recent evidence concerning the relationship between the exposure to organic solvents and the impairment of colour vision.
A bibliographic search was conducted for scientific papers published in the last 15 years, in the LILACS, PubMed, Science Direct, EBSCO, and Cochrane databases that included observational studies assessing the relationship between impairment in colour vision and exposure to organic solvents.
Eleven studies were selected that were performed on an economically active population and used the Lanthony D-15 desaturated test (D-15d), measured the exposure to organic solvents, and included unexposed controls. It was found that there is a statistically significant relationship between the exposure to organic solvents and the presence of an impairment in colour vision.
The results support the hypothesis that exposure to organic solvents could induce acquired dyschromatopsia. The evaluation of colour vision with the D-15d test is simple and sensitive for diagnosis. More studies need to be conducted on this subject in order to better understand the relationship between impaired colour vision and more severe side effects caused by this exposure.
评估近期有关有机溶剂暴露与色觉损害之间关系的证据。
在LILACS、PubMed、Science Direct、EBSCO和Cochrane数据库中对过去15年发表的科学论文进行文献检索,这些论文包括评估色觉损害与有机溶剂暴露之间关系的观察性研究。
选择了11项针对经济活跃人群开展的研究,这些研究使用了兰托尼D - 15去饱和试验(D - 15d),测量了有机溶剂暴露情况,并纳入了未暴露的对照组。结果发现,有机溶剂暴露与色觉损害之间存在统计学上的显著关系。
这些结果支持有机溶剂暴露可能诱发后天性色觉障碍的假说。使用D - 15d试验评估色觉简单且对诊断敏感。为了更好地理解色觉损害与这种暴露所导致的更严重副作用之间的关系,需要对此主题开展更多研究。