Guérin J M, Meyer P, Segrestaa J M, Reizine D, Levy C
Centre de Réanimation, Clinique Thérapeutique, Hôpital Lariboisière, Paris.
Ann Med Interne (Paris). 1989;140(2):106-7.
The authors studied the frequency of sinusitis in nasotracheally intubated patients in an Intensive Care Unit. All patients intubated nasotracheally during an 8 day period were included in a prospective study which included CT scanning with views of all the paranasal sinuses. Sinusitis was defined as opacification of the sinus with an air-fluid level. Transantral punctures were performed in cases of maxillary sinusitis. Fifty-three patients were included. Local symptoms and/or unexplained fever were present in 22% of cases. CT scanning showed sinusitis in 49 of the 53 cases (pansinusitis 42 cases, maxillary alone 5 cases, sphenoidal 16 cases). Bacteriological cultures of sinus punctures were positive in 39 cases, monomicrobial in 21 and polymicrobial in 18 cases. Twenty of the 53 patients developed a lower respiratory tract infection with the same germ and 10 developed septicemia (3 with isolated sinusitis and 7 with pneumonia). Eighteen patients died (6 of their infection and 12 of the underlying disease). This study shows the high frequency of bacterial sinusitis and the necessity of sinus puncture for bacteriological identification of the causal organism to adapt antibiotic therapy.
作者研究了重症监护病房中经鼻气管插管患者鼻窦炎的发生率。在一项前瞻性研究中纳入了所有在8天期间内经鼻气管插管的患者,该研究包括对所有鼻窦进行CT扫描。鼻窦炎定义为鼻窦出现气液平面的混浊。对于上颌窦炎患者进行经鼻窦穿刺。共纳入53例患者。22%的病例出现局部症状和/或不明原因发热。CT扫描显示53例中有49例存在鼻窦炎(全鼻窦炎42例,单纯上颌窦炎5例,蝶窦炎16例)。鼻窦穿刺的细菌培养39例呈阳性,其中21例为单一微生物感染,18例为多微生物感染。53例患者中有20例发生了由相同病原体引起的下呼吸道感染,10例发生败血症(3例为单纯鼻窦炎,7例为肺炎)。18例患者死亡(6例死于感染,12例死于基础疾病)。这项研究表明细菌性鼻窦炎的发生率很高,以及为了确定病原体以调整抗生素治疗而进行鼻窦穿刺的必要性。