Meyer P, Guérin J M, Habib Y, Lévy C
Clinique Thérapeutique, Hôpital Lariboisière, Paris.
Ann Fr Anesth Reanim. 1988;7(1):26-30. doi: 10.1016/s0750-7658(88)80008-x.
Nosocomial pneumonia is a frequent infectious complication in ICU patients. All the patients with prolonged nasotracheal intubation presenting with nosocomial pneumonia according to Salata's criteria were examined for sinusitis in the prospective study. Diagnosis was confirmed via CT-scan views and transnasal sinus puncture. In eleven nasally intubated patients, CT-scan views showed air fluid levels and multiple sinus involvement. Bacteriological studies isolated the same gram negative bacilli in both sinus and bronchial aspirates. In four cases, a polymicrobial sinusitis was found with a single organism predominant. This predominant germ was always found in bronchial aspirate. Recovery from pneumonia was obtained only after sinus drainage. Treatment included removing the nasal tubes, or performing tracheostomy and systemic antibiotics. One patient required surgical maxillary sinus drainage after failure of medical management. The occurrence of nosocomial pneumonia in nasotracheally intubated patients should lead physicians to explore the paranasal sinuses. Sinus CT-scan views should be routinely obtained in the assessment of pulmonary sepsis in patients with prolonged nasotracheal intubation. Persistent or ignored nosocomial sinusitis in such circumstances could be a major source of treatment failure.
医院获得性肺炎是重症监护病房(ICU)患者常见的感染性并发症。在这项前瞻性研究中,对所有根据萨拉塔标准诊断为医院获得性肺炎且长期经鼻气管插管的患者进行了鼻窦炎检查。通过CT扫描和经鼻鼻窦穿刺确诊。在11例经鼻插管患者中,CT扫描显示有气液平面和多个鼻窦受累。细菌学研究在鼻窦和支气管吸出物中分离出相同的革兰氏阴性杆菌。在4例患者中,发现为多微生物性鼻窦炎,以单一微生物为主。这种主要病菌在支气管吸出物中总是能找到。只有在鼻窦引流后肺炎才得以康复。治疗包括拔除鼻导管、行气管切开术及全身使用抗生素。1例患者药物治疗失败后需要进行上颌窦手术引流。经鼻气管插管患者发生医院获得性肺炎应促使医生检查鼻窦。对于长期经鼻气管插管的患者,在评估肺部感染时应常规进行鼻窦CT扫描。在这种情况下,持续存在或被忽视的医院获得性鼻窦炎可能是治疗失败的主要原因。