1 PsyQ Expertise Center Adult ADHD, The Hague, The Netherlands.
2 VU University Medical Center, Amsterdam, The Netherlands.
J Atten Disord. 2018 Mar;22(5):460-471. doi: 10.1177/1087054716659137. Epub 2016 Jul 14.
ADHD may predispose to obesity, a metabolic syndrome component. Affective disorders are also associated with MetSyn and ADHD. This study examined whether ADHD confers any added risk of MetSyn and obesity-related associations in a large sample with varying stages of affective disorders.
Participants included 2,303 adults from the Netherlands Study of Depression and Anxiety. Three groups were compared (controls, those with depressive/anxiety disorders without ADHD; and those with depressive/anxiety disorders and ADHD) for presence of MetSyn risk factors, body mass index, and waist-hip ratio. ADHD symptoms were identified by using a T-score > 65 (Conners Adult ADHD Rating Scale).
Multivariable analyses were additionally adjusted for sociodemographic, lifestyle, health factors, and affective disorders. Analyses showed no significant association between MetSyn, obesity-related variables, and comorbid ADHD. High Inattention and Hyperactivity/Impulsivity symptoms were not associated with MetSyn.
This study did not confirm that MetSyn and obesity-related parameters are increased in comorbid ADHD.
ADHD 可能导致肥胖，肥胖是代谢综合征的一个组成部分。情感障碍也与 MetSyn 和 ADHD 有关。本研究在一个具有不同阶段情感障碍的大样本中，考察了 ADHD 是否会对 MetSyn 和肥胖相关的关联产生任何额外的风险。
参与者包括来自荷兰抑郁与焦虑研究的 2303 名成年人。将三组进行比较（对照组、无 ADHD 的抑郁/焦虑障碍组和有 ADHD 的抑郁/焦虑障碍组），比较 MetSyn 风险因素、体重指数和腰臀比。使用 T 分数>65（Conners 成人 ADHD 评定量表）来确定 ADHD 症状。
多变量分析还针对社会人口统计学、生活方式、健康因素和情感障碍进行了调整。分析显示，MetSyn、肥胖相关变量与共病 ADHD 之间没有显著关联。高注意力不集中和多动/冲动症状与 MetSyn 无关。
本研究并未证实共病 ADHD 会增加 MetSyn 和肥胖相关参数。
