Sahuguède P, Roisin A, Sanou I, Nacro B, Tall F
Ann Pediatr (Paris). 1989 Apr;36(4):244-51.
From January 1986 through June 1987, 714 children with measles were admitted to the Pediatric Department of the Sanou Souro Hospital in Bobo-Dioulasso, Burkina-Faso. Eighty-four per cent of cases occurred during the first semester of 1987. Sixty per cent of patients were 9 to 35 months of age. The case-fatality rate was 29.1% (31.5% during the first semester of 1987, 12% in 1986). Fifty-five per cent of deaths occurred within 24 hours of admission. The most common clinical features upon admission included dehydration (91% of patients), diarrhea (64%), conjunctivitis (56%), fever in excess of 39.5 degrees C (50%), respiratory infection (46%), and cardiovascular collapse (34.5%). Factors associated with a fatal outcome included dehydration and cardiovascular collapse, poor nutritional status, and occurrence of the disease during the dry season (March, April, May). In most cases, immunization status of affected children was unknown. The high mortality rate can be ascribed to the significant delay with which medical care was provided, due in part to the inadequacy of primary health care facilities. This outbreak denotes the inadequacy of immunization against this disease that is included in the Extended Immunization Program.
1986年1月至1987年6月期间,714名麻疹患儿被收治于布基纳法索博博迪乌拉索的萨努·苏罗医院儿科。84%的病例发生在1987年第一学期。60%的患者年龄在9至35个月之间。病死率为29.1%(1987年第一学期为31.5%,1986年为12%)。55%的死亡发生在入院后24小时内。入院时最常见的临床特征包括脱水(91%的患者)、腹泻(64%)、结膜炎(56%)、体温超过39.5摄氏度(50%)、呼吸道感染(46%)和心血管衰竭(34.5%)。与致命结局相关的因素包括脱水和心血管衰竭、营养状况差以及疾病在旱季(3月、4月、5月)发生。在大多数情况下,受影响儿童的免疫接种状况不明。高死亡率可归因于医疗救治的显著延迟,部分原因是初级卫生保健设施不足。此次疫情表明扩大免疫规划中针对该疾病的免疫接种存在不足。