Singh J, Sharma R S, Verghese T
National Institute of Communicable Diseases, Delhi.
J Commun Dis. 1994 Dec;26(4):203-14.
This paper reviews the measles Case Fatality Ratios (CFRs) reported in the community based studies from India. Measles mortality varied considerably in outbreaks, prospective and retrospective studies. A median CFR of 2.5 per cent (0.2-3.7), 0.1 per cent (0-2.2) and 3.7 per cent (0-23.9) was recorded in prospective, retrospective and outbreak studies respectively. The retrospective studies seem to underestimate the measles mortality in Indian setting. Most of the outbreaks recording CFRs equal to or less than the median, 3.7 per cent, occurred in the areas where health care facilities were available for treatment of measles associated complications. Virtually in all studies, the age specific CFRs wherever recorded, were found to be the highest among infants and thereafter the ratios declined progressively. Although suggestive of, the studies did not provide sufficient data to establish an association between malnourishment and the risk of dying from measles. Measles mortality was not consistently high in any particular sex. The study makes a strong case for measles immunization at the earliest recommended age and the provision of better health services as the important public health measures for reducing the measles CFRs.
本文回顾了印度基于社区的研究中报告的麻疹病死率(CFRs)。在疫情、前瞻性和回顾性研究中,麻疹死亡率差异很大。前瞻性、回顾性和疫情研究中记录的CFR中位数分别为2.5%(0.2 - 3.7)、0.1%(0 - 2.2)和3.7%(0 - 23.9)。回顾性研究似乎低估了印度环境下的麻疹死亡率。大多数记录的CFR等于或低于中位数3.7%的疫情发生在有医疗设施可用于治疗麻疹相关并发症的地区。实际上在所有研究中,无论何处记录的年龄特异性CFR在婴儿中最高,此后该比率逐渐下降。尽管有提示,但这些研究没有提供足够的数据来确定营养不良与麻疹死亡风险之间的关联。麻疹死亡率在任何特定性别中都并非一直很高。该研究有力地说明了尽早在推荐年龄进行麻疹免疫接种以及提供更好的卫生服务作为降低麻疹CFRs的重要公共卫生措施。