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[布博迪乌拉索(布基纳法索)儿科医院的急性呼吸道感染]

[Acute respiratory infections in pediatric hospital at Bobo-Dioulasso (Burkina Faso)].

作者信息

Tall F R, Valian A, Curtis V, Traore A, Nacro B, Cousens S, Diallo I, Traore E, Mertens T H

机构信息

Service de pédiatrie, centre hospitalier national Souro-Sanou, Bobo-Dioulasso, Burkina Faso.

出版信息

Arch Pediatr. 1994 Mar;1(3):249-54.

PMID:7994332
Abstract

BACKGROUND

Acute lower respiratory tract infections are the primary cause of morbidity in developing countries.

POPULATION AND METHODS

Six hundred and sixty seven children (379 boys, 288 girls, aged 0-30 months) admitted for lower respiratory tract infections from January 1990 to March 1991 were included in the study. Immediate medical history was collected from the mother. The weight, height, temperature and clinical manifestations, plus the results of chest X-rays, parasitologic and bacteriological examination of stools, and blood smear for malaria were recorded for each patient. Sero-immunologic study for HIV infection of 473 of the patients aged 12-36 months and their mothers also took part in a sero-immunological study for HIV infection.

RESULTS

Lower respiratory tract infections were the second major cause of admission (16.8%) after malaria (28.7%). Infections peaked between 6 and 11 months of age (29.5%). The main diseases were pneumonia and bronchial pneumonia (54%) followed by bronchiolitis (21.7%). Almost half the patients were admitted during the hot, dry season. Two hundred and eighty seven patients (43.4%) were referred only after they had been suffering from the disease for 3 to 9 days, partly explaining the high level of mortality. One hundred and twenty one patients (20.9%) died; the main cause of death was staphylococcal pneumonia (57.9%), followed by pneumonia and bronchial pneumonia (29.3%). Some criteria for severity could be identified, based on pulmonary signs and symptoms and associated manifestations (dehydration, malnutrition, convulsions, anemia). Twenty two patients were positive for HIV-1 infection.

CONCLUSIONS

This study confirms that acute lower respiratory tract infections remain a public health problem. Early diagnosis and treatment are necessary to reduce mortality.

摘要

背景

急性下呼吸道感染是发展中国家发病的主要原因。

研究对象与方法

本研究纳入了1990年1月至1991年3月因下呼吸道感染入院的667名儿童(379名男孩,288名女孩,年龄0至30个月)。从母亲处收集近期病史。记录每位患者的体重、身高、体温、临床表现,以及胸部X光检查结果、粪便寄生虫和细菌学检查结果,还有疟疾血涂片检查结果。对473名12至36个月大的患者及其母亲进行了HIV感染的血清免疫学研究。

结果

下呼吸道感染是继疟疾(28.7%)之后的第二大入院原因(16.8%)。感染在6至11个月大时达到高峰(29.5%)。主要疾病是肺炎和支气管肺炎(54%),其次是细支气管炎(21.7%)。几乎一半的患者在炎热干燥季节入院。287名患者(43.4%)在患病3至9天后才转诊,这部分解释了高死亡率的原因。121名患者(20.9%)死亡;主要死亡原因是葡萄球菌肺炎(57.9%),其次是肺炎和支气管肺炎(29.3%)。根据肺部体征和症状以及相关表现(脱水、营养不良、惊厥、贫血)可以确定一些严重程度标准。22名患者HIV-1感染呈阳性。

结论

本研究证实急性下呼吸道感染仍然是一个公共卫生问题。早期诊断和治疗对于降低死亡率是必要的。

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