Motie Mohammad Reza, Hashemi Parham
Department of General Surgery, Surgical Oncology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Acta Med Iran. 2016 Jul;54(7):437-40.
To determine whether the medical Treatment of anal fissure can be an effective alternative for surgery Methods: Retrospectively, we randomly selected 190 Patients being treated for anal fissure between the years 2005-2010 in 3 equal groups: group A: Patients who received medical treatment with topical nitroglycerin, group B: Patient treated with topical diltiazem, and group C: Patients underwent surgery. The results were then correlated with the statistical program SPSS using chi-square test. Main complaints of the patients were first anal pain and then bleeding. The response to treatments for relieving pain was: 77% in A, 83% in B, and 98% in group C. Response of treatments for fissure healing, in order of groups A, B and C was: 74%, 83%, and 94%. Despite good response to medical treatment, surgical treatment was more effective and medical treatment of choice in patients who are willing to have surgery.
为确定肛裂的药物治疗是否可作为手术的有效替代方法,方法:我们回顾性地随机选取了2005年至2010年间接受肛裂治疗的190例患者,分为3组,每组人数相等:A组:接受局部硝酸甘油药物治疗的患者;B组:接受局部地尔硫䓬治疗的患者;C组:接受手术治疗的患者。然后使用卡方检验将结果与统计软件SPSS相关联。患者的主要主诉先是肛门疼痛,然后是出血。治疗缓解疼痛的有效率为:A组77%,B组83%,C组98%。肛裂愈合的治疗有效率,按A、B、C组顺序依次为:74%、83%和94%。尽管药物治疗反应良好,但手术治疗更有效,对于愿意接受手术的患者,手术是首选治疗方法。