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慢性肛裂:药物治疗与手术括约肌切开术的对比研究

Chronic Anal Fissure: A Comparative Study of Medical Treatment Versus Surgical Sphincterotomy.

作者信息

Motie Mohammad Reza, Hashemi Parham

机构信息

Department of General Surgery, Surgical Oncology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

出版信息

Acta Med Iran. 2016 Jul;54(7):437-40.

Abstract

To determine whether the medical Treatment of anal fissure can be an effective alternative for surgery Methods: Retrospectively, we randomly selected 190 Patients being treated for anal fissure between the years 2005-2010 in 3 equal groups: group A: Patients who received medical treatment with topical nitroglycerin, group B: Patient treated with topical diltiazem, and group C: Patients underwent surgery. The results were then correlated with the statistical program SPSS using chi-square test. Main complaints of the patients were first anal pain and then bleeding. The response to treatments for relieving pain was: 77% in A, 83% in B, and 98% in group C. Response of treatments for fissure healing, in order of groups A, B and C was: 74%, 83%, and 94%. Despite good response to medical treatment, surgical treatment was more effective and medical treatment of choice in patients who are willing to have surgery.

摘要

为确定肛裂的药物治疗是否可作为手术的有效替代方法,方法:我们回顾性地随机选取了2005年至2010年间接受肛裂治疗的190例患者,分为3组,每组人数相等:A组:接受局部硝酸甘油药物治疗的患者;B组:接受局部地尔硫䓬治疗的患者;C组:接受手术治疗的患者。然后使用卡方检验将结果与统计软件SPSS相关联。患者的主要主诉先是肛门疼痛,然后是出血。治疗缓解疼痛的有效率为:A组77%,B组83%,C组98%。肛裂愈合的治疗有效率,按A、B、C组顺序依次为:74%、83%和94%。尽管药物治疗反应良好,但手术治疗更有效,对于愿意接受手术的患者,手术是首选治疗方法。

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