Adegboyega Titilayo O, Borgert Andrew J, Lambert Pamela J, Jarman Benjamin T
Department of Medical Education, Gundersen Medical Foundation, La Crosse, WI, USA.
Department of Research, Gundersen Medical Foundation, La Crosse, WI, USA.
Am J Surg. 2017 Jan;213(1):30-35. doi: 10.1016/j.amjsurg.2016.04.011. Epub 2016 Jun 14.
Discussing potential morbidity and mortality is essential to informed decision-making and consent. The American College of Surgery National Surgical Quality Improvement Program developed an online risk calculator (RC) using patient-specific information to determine operative risk.
Colorectal procedures at our independent academic medical center from 2010 to 2011 were evaluated. The RC's predicted outcomes were compared with observed outcomes. Statistical analysis included Brier score, Wilcoxon sign rank test, and standardized event ratio.
There were 324 patients included. The RC's Brier score was .24 (.015-.219) for predicting mortality and morbidity, respectively. The observed event rate for surgical site infection and any complication was higher than the RC predicted (standardized event ratio 1.9 CI [1.49 to 2.39] and 1.39 CI [1.14 to 1.68], respectively). The observed length of stay was longer than predicted (5.6 vs 6.6 days, P < .001).
The RC underestimated the surgical site infection and overall complication rates. The RC is a valuable tool in predicting risk for adverse outcomes; however, institution-specific trends may influence actual risk. Surgeons and institutions must recognize areas where they are outliers from estimated risks and tailor risk discussions accordingly.
讨论潜在的发病率和死亡率对于做出明智的决策和获得知情同意至关重要。美国外科医师学会国家外科质量改进计划开发了一种在线风险计算器(RC),利用患者的具体信息来确定手术风险。
对我们独立的学术医疗中心2010年至2011年的结直肠手术进行了评估。将RC预测的结果与观察到的结果进行比较。统计分析包括Brier评分、Wilcoxon符号秩检验和标准化事件比率。
共纳入324例患者。RC预测死亡率和发病率的Brier评分分别为0.24(0.015 - 0.219)。手术部位感染和任何并发症的观察事件发生率高于RC预测值(标准化事件比率分别为1.9 CI [1.49至2.39]和1.39 CI [1.14至1.68])。观察到的住院时间比预测的更长(5.6天对6.6天,P < 0.001)。
RC低估了手术部位感染率和总体并发症发生率。RC是预测不良结局风险的一个有价值的工具;然而,特定机构的趋势可能会影响实际风险。外科医生和机构必须认识到他们与估计风险不同的领域,并相应地调整风险讨论。