颈段脊髓孤立性血管母细胞瘤：一例报告及文献复习
Isolated hemangioblastoma of the cervical spinal cord: A case report and literature review.
作者信息
Vo Dat T, Cravens George F, Germann Robert E
机构信息
Department of Pediatrics, John Peter Smith Hospital, 1500 South Main Street, Fort Worth, TX 76104, United States; Department of Neurosurgery, John Peter Smith Hospital, 1500 South Main Street, Fort Worth, TX 76104, United States; The Center for Neurological Disorders, 1010 Houston Street, Fort Worth, TX 76102, United States; Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX 75390, United States.
Department of Neurosurgery, John Peter Smith Hospital, 1500 South Main Street, Fort Worth, TX 76104, United States; The Center for Neurological Disorders, 1010 Houston Street, Fort Worth, TX 76102, United States.
出版信息
Int J Surg Case Rep. 2016;26:7-11. doi: 10.1016/j.ijscr.2016.07.002. Epub 2016 Jul 6.
INTRODUCTION
Hemangioblastomas are benign, slow growing but highly vascularized tumors of the central nervous system, with the most common location of occurrence in the posterior fossa. Hemangioblastomas usually have an associated with patients that have Von-Hippel Lindau disease, resulting a germline mutation in the VHL tumor suppressor gene. Isolated or sporadic occurrences of hemangioblastomas are much more infrequent and typically respond well after surgery.
PRESENTATION OF CASE
We present case of a 22year old female with worsening shoulder pain, decreased sensation in the hands and feet, and decreasing strength and was found to have a hemangioblastoma of the cervical spine.
DISCUSSION
The patient was treated with surgery and responded well to treatment. We also present a review of the literature on isolated occurrences of hemangioblastomas of the spinal cord.
CONCLUSION
Isolated hemangioblastoma are a rare tumor of the central nervous system and can be managed with surgery.
引言
血管母细胞瘤是中枢神经系统的良性、生长缓慢但血管高度丰富的肿瘤，最常见于后颅窝。血管母细胞瘤通常与患有冯·希佩尔-林道病的患者有关，这会导致VHL肿瘤抑制基因发生种系突变。孤立性或散发性血管母细胞瘤的发生更为罕见，通常手术后反应良好。
病例介绍
我们报告一例22岁女性患者，其肩部疼痛加重、手脚感觉减退、肌力下降，被发现患有颈椎血管母细胞瘤。
讨论
该患者接受了手术治疗，治疗反应良好。我们还对脊髓孤立性血管母细胞瘤的文献进行了综述。
结论
孤立性血管母细胞瘤是一种罕见的中枢神经系统肿瘤，可通过手术治疗。
Zotero 插件