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Community Dent Oral Epidemiol. 2010 Jun;38(3):274-86. doi: 10.1111/j.1600-0528.2010.00532.x. Epub 2010 Mar 26.
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Interleukin-8 is increased in gingival crevicular fluid from patients with acute pulpitis.
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Injection pain of the inferior alveolar nerve block in patients with irreversible pulpitis.不可逆性牙髓炎患者下牙槽神经阻滞麻醉的注射痛
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Substance P receptor expression in healthy and inflamed human pulp tissue.P物质受体在健康和炎症状态下的人牙髓组织中的表达
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The efficacy comparison of ibuprofen, acetaminophen-codeine, and placebo premedication therapy on the depth of anesthesia during treatment of inflamed teeth.布洛芬、对乙酰氨基酚-可待因和安慰剂术前用药疗法对发炎牙齿治疗期间麻醉深度的疗效比较。
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拔牙后疼痛与急性牙髓炎之间的关系：一项使用第三磨牙的随机试验。

Relationship between post-extraction pain and acute pulpitis: a randomised trial using third molars.

作者信息

Zhang Wei, Dai Yong-Bo, Wan Peng-Cheng, Xu Dong-Dong, Guo Yi, Li Zhi

机构信息

Department of Endodontics, School and Hospital of Stomatology, Wuhan University, Wuhan, China.

The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) and Key Laboratory for Oral Biomedical Engineering of the Ministry of Education, Wuhan University, Wuhan, China.

出版信息

Int Dent J. 2016 Dec;66(6):325-329. doi: 10.1111/idj.12249. Epub 2016 Jul 18.

DOI:10.1111/idj.12249
PMID:27424879
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9376631/
Abstract

INTRODUCTION

The aim of the present study was to examine the relationship between post-extraction pain and acute pulpitis in third molars.

METHODS

This study was a randomised controlled trial. Sixty patients requiring removal of a single maxillary third molar with acute pulpitis were included and randomly divided into two groups: group A (n = 30); and group B (n = 30). In group A, third molars were directly extracted, and group B received endodontic therapy (pulp chamber opening and drainage) and underwent extraction 24 hours later, aiming to eliminate the acute inflammation. Another 30 patients requiring removal of a single maxillary third molar and with the same inclusion criteria but without caries or acute pulpitis were recruited into group C, in which the maxillary third molars were also directly extracted. The level of postoperative pain reported each day among the three groups was statistically evaluated.

RESULTS

On the first, second and third days after surgery, there was a statistically significant difference between group A and group B and between group A and group C, but there was no statistically significant difference between group B and group C.

CONCLUSION

The results of the present study indicate that there is more pain when third molars with acute pulpitis are directly removed compared with the pain level of the removal of third molars without acute pulpitis.

摘要

引言

本研究的目的是探讨第三磨牙拔除术后疼痛与急性牙髓炎之间的关系。

方法

本研究为随机对照试验。纳入60例需要拔除单个上颌第三磨牙且患有急性牙髓炎的患者，并随机分为两组：A组（n = 30）；B组（n = 30）。A组直接拔除第三磨牙，B组接受牙髓治疗（开髓引流），24小时后进行拔除，旨在消除急性炎症。另外30例需要拔除单个上颌第三磨牙且符合相同纳入标准但无龋齿或急性牙髓炎的患者被纳入C组，C组上颌第三磨牙也直接拔除。对三组患者术后每天报告的疼痛程度进行统计学评估。

结果

术后第一天、第二天和第三天，A组与B组之间以及A组与C组之间存在统计学显著差异，但B组与C组之间无统计学显著差异。

结论

本研究结果表明，与拔除无急性牙髓炎的第三磨牙相比，直接拔除患有急性牙髓炎的第三磨牙时疼痛更剧烈。