Kaminskiĭ Iu V, Kolesnnikov V I
Arkh Patol. 1989;51(4):9-15.
The microcirculatory bed (MCB) and smooth muscle cells (SMC) of the main arteries were examined in subjects who had died from rheumatic disease (33 cases), systemic lupus erythematosus (n = 28), and systemic sclerosis (n = 8) at the age of 12 to 69 years. Adventitial film preparations impregnated with silver nitrate by the method of Kupriyanov and other techniques were applied to comparatively characterize pathological and adaptive changes in MCB of vasa vasorum. In each disease, there were impaired smooth cells along with formed SMC deficit that was mostly pronounced in lupus. The medial SMC were shown to contribute to the degradation of the basic substance and reparative and synthetic processes. It was found that the immune complexes might be accepted both by the vasa vasorum system and the luminal surface of large arteries.
对12至69岁死于风湿性疾病(33例)、系统性红斑狼疮(n = 28)和系统性硬化症(n = 8)的受试者的主动脉微血管床(MCB)和平滑肌细胞(SMC)进行了检查。采用库普里亚诺夫法等技术制备硝酸银浸渍的外膜片,以比较表征血管滋养管MCB的病理和适应性变化。在每种疾病中,均存在平滑肌细胞受损以及SMC缺失,这在狼疮中最为明显。已表明中膜SMC参与了基质的降解以及修复和合成过程。研究发现,血管滋养管系统和大动脉管腔表面均可接受免疫复合物。