Karle E J, Gehring F
Dtsch Zahnarztl Z. 1978 Mar;33(3):189-91.
By means of programmed feeding experiments on rats, the caries-producing properties of a new sugar substitute Palat-nit were compared with those of other carbohydrates. The cariogenicity of Palatinit was significantly lower than that of sucrose and lactose and roughly comparable to that of L-sorbose. Reference strains of s. mutans are unable to produce extra-cellular polysaccharide or notable amounts of acid from Palatinit. The use of this substance as sugar substitute can be recommended for caries prophylaxis on the basis of these experiments.
通过对大鼠进行程序化喂养实验,将一种新型糖替代品帕拉金糖醇(Palat-nit)的致龋特性与其他碳水化合物的致龋特性进行了比较。帕拉金糖醇的致龋性明显低于蔗糖和乳糖,大致与L-山梨糖相当。变形链球菌的参考菌株无法利用帕拉金糖醇产生细胞外多糖或大量酸。基于这些实验,可推荐使用这种物质作为糖替代品用于预防龋齿。