Sesti Joanna, Donington Jessica S
Department of Cardiothoracic Surgery, NYU School of Medicine, 530 1st Avenue, Suite 9V, New York, NY 10016, USA.
Department of Cardiothoracic Surgery, NYU School of Medicine, 530 1st Avenue, Suite 9V, New York, NY 10016, USA.
Thorac Surg Clin. 2016 Aug;26(3):251-9. doi: 10.1016/j.thorsurg.2016.04.007.
Despite a prospective randomized trial that reported decreased locoregional recurrence for the intentional use of sublobar resection for stage IA non-small cell lung cancer, it continues to be a point of considerable debate. Improved imaging techniques have introduced a large group of smaller and more indolent tumors than what was studied 20 years ago by the Lung Cancer Study Group. Multiple single-institution and population-based analyses suggest that sublobar resections may have equivalent outcomes to lobectomy in well-selected patients with small (<2 cm) resections, and in whom an adequate resection margin can be achieved.
尽管一项前瞻性随机试验报告称，对于IA期非小细胞肺癌有意使用亚肺叶切除术可降低局部区域复发率，但这一问题仍存在大量争议。与20年前肺癌研究组所研究的情况相比，改进后的成像技术发现了一大批更小、生长更缓慢的肿瘤。多项单机构和基于人群的分析表明，对于精心挑选的、肿瘤较小（<2 cm）且能实现足够切缘的患者，亚肺叶切除术的效果可能与肺叶切除术相当。
