Romeo Umberto, Nardi Gianna Maria, Libotte Fabrizio, Sabatini Silvia, Palaia Gaspare, Grassi Felice Roberto
Department of Oral and Maxillofacial Sciences, "Sapienza" University of Rome, Via Caserta 6, 00161 Rome, Italy.
University of Bari, Piazza Umberto I, 70121 Bari, Italy.
Int J Dent. 2016;2016:7692387. doi: 10.1155/2016/7692387. Epub 2016 Jun 26.
Introduction. The aim of this study is to demonstrate the effectiveness of addition of the antimicrobial photodynamic therapy to the conventional approach in the treatment of peri-implantitis. Materials and Methods. Forty patients were randomly assigned to test or control groups. Patients were assessed at baseline and at six (T1), twelve (T2), and twenty-four (T3) weeks recording plaque index (PlI), probing pocket depth (PPD), and bleeding on probing (BOP); control group received conventional periodontal therapy, while test group received photodynamic therapy in addition to it. Result. Test group showed a 70% reduction in the plaque index values and a 60% reduction in PD values compared to the baseline. BOP and suppuration were not detectable. Control group showed a significative reduction in plaque index and PD. Discussion. Laser therapy has some advantages in comparison to traditional therapy, with faster and greater healing of the wound. Conclusion. Test group showed after 24 weeks a better value in terms of PPD, BOP, and PlI, with an average pocket depth value of 2 mm, if compared with control group (3 mm). Our results suggest that antimicrobial photodynamic therapy with diode laser and phenothiazine chloride represents a reliable adjunctive treatment to conventional therapy. Photodynamic therapy should, however, be considered a coadjuvant in the treatment of peri-implantitis associated with mechanical (scaling) and surgical (grafts) treatments.
引言。本研究的目的是证明在种植体周炎治疗中，在传统方法基础上添加抗菌光动力疗法的有效性。材料与方法。40例患者被随机分为试验组和对照组。在基线以及6周（T1）、12周（T2）和24周（T3）时对患者进行评估，记录菌斑指数（PlI）、探诊袋深度（PPD）和探诊出血（BOP）；对照组接受传统牙周治疗，而试验组在此基础上还接受光动力治疗。结果。与基线相比，试验组的菌斑指数值降低了70%，PD值降低了60%。未检测到BOP和化脓情况。对照组的菌斑指数和PD有显著降低。讨论。与传统治疗相比，激光治疗具有一些优势，伤口愈合更快且更明显。结论。与对照组（3mm）相比，试验组在24周后在PPD、BOP和PlI方面表现出更好的值，平均袋深值为2mm。我们的结果表明，使用二极管激光和氯化吩噻嗪的抗菌光动力疗法是传统治疗的一种可靠辅助治疗方法。然而，在与机械（洁治）和手术（植骨）治疗相关的种植体周炎治疗中，光动力疗法应被视为一种辅助治疗方法。
