Malik Rajvir, Manocha Anish, Suresh D K
Department of Periodontics and Oral Implantology, M.M. College of Dental Sciences and Research, M.M. University, Mullana, Ambala, Haryana-133 203, India.
Indian J Dent Res. 2010 Apr-Jun;21(2):285-91. doi: 10.4103/0970-9290.66659.
Mechanical removal of the biofilm and adjunctive use of antibacterial disinfectants or various antibiotics have been conventional methods of the periodontitis therapy. There has been an upsurge of bacterial strains becoming resistant due to the injudicious use of antibiotics, recently. As a result there is pronounced interest and keenness in the development of alternate antimicrobial concepts. As the scientific community seeks alternatives to antibiotic treatment, periodontal researchers have found that photodynamic therapy (PDT) is advantageous to suppress anaerobic bacteria. Hence, PDT could be an alternative to conventional periodontal therapeutic methods. This review elucidates the evolution and use of photo dynamic therapy. The application of photosensitizing dyes and their excitation by visible light enables effective killing of periodontopathogens. Even though PDT is still in the experimental stages of development and testing, the method may be an adjunct to conventional antibacterial measures in periodontology. PDT application has an adjunctive benefit besides mechanical treatment at sites with difficult access. Necessity for flap operations may be reduced, patient comfort may increase and treatment time decrease. Clinical follow-up studies are needed to confirm the efficacy of the procedure.
机械清除生物膜以及辅助使用抗菌消毒剂或各种抗生素一直是牙周炎治疗的传统方法。近来，由于抗生素的不当使用，出现了越来越多具有耐药性的细菌菌株。因此，人们对开发替代抗菌概念表现出浓厚的兴趣和热情。随着科学界寻求抗生素治疗的替代方法，牙周病研究人员发现光动力疗法（PDT）在抑制厌氧菌方面具有优势。因此，PDT可能成为传统牙周治疗方法的替代方案。这篇综述阐明了光动力疗法的发展历程及应用。光敏染料的应用及其通过可见光激发能够有效杀灭牙周病原体。尽管PDT仍处于研发和测试的实验阶段，但该方法可能成为牙周病学中传统抗菌措施的辅助手段。在难以到达的部位，PDT应用除了机械治疗外还有辅助益处。可能减少翻瓣手术的必要性，提高患者舒适度并缩短治疗时间。需要进行临床随访研究以证实该程序的疗效。
