Enderle J D, Engelken E J, Stiles R N
Biomed Sci Instrum. 1989;25:155-61.
Agonist and antagonist muscle tension simulations are reported for a fourth-order model of the oculomotor plant and active state tensions generated by a neural feedback model during horizontal saccadic eye movements. The lateral and medial rectus muscles are modeled as a parallel combination of passive elasticity, and series elasticity connected to a parallel combination of active state tension generator, viscosity element and elastic element. The eyeball is modeled as a sphere with moment of inertia connected to a viscosity element and an elastic element. The active state tension is generated by a low-pass filtered output from the neural burst circuit. The saccade generator is first-order time optimal and located in the superior colliculus. Agonist muscle tensions simulated with TUTSIM match the data extremely well. Antagonist muscle tension simulated with TUTSIM have an initial drop in tension, consistent with microelectrode predictions, and then a rise in muscle tension. The initial drop in antagonist muscle tension has not been reported in the literature because of band limitations of the force transducer used to record muscle tension.
报告了用于眼球运动装置的四阶模型的激动剂和拮抗剂肌肉张力模拟，以及水平扫视眼动期间神经反馈模型产生的活动状态张力。外直肌和内直肌被建模为被动弹性的并联组合，以及与活动状态张力发生器、粘性元件和弹性元件的并联组合相连的串联弹性。眼球被建模为一个具有转动惯量的球体，与一个粘性元件和一个弹性元件相连。活动状态张力由神经爆发电路的低通滤波输出产生。扫视发生器是一阶时间最优的，位于上丘。用TUTSIM模拟的激动剂肌肉张力与数据匹配得非常好。用TUTSIM模拟的拮抗剂肌肉张力在张力上有一个初始下降，与微电极预测一致，然后肌肉张力上升。由于用于记录肌肉张力的力传感器的带宽限制，拮抗剂肌肉张力的初始下降在文献中尚未报道。
