单次放射治疗对患有肘部骨关节炎犬负重性跛行的影响。

Effect of single dose radiation therapy on weight-bearing lameness in dogs with elbow osteoarthritis.

作者信息

Kapatkin Amy S, Nordquist Barbro, Garcia Tanya C, Griffin Maureen A, Theon Alain, Kim Sun, Hayashi Kei

机构信息

Dr. Amy Kapatkin, University of California-Davis, Surgical & Radiological Sciences, 2112 Tupper Hall, Davis, California 95616, United States, Phone: +1 530 752 6787, Fax: +1 530 752 6042, Email:

出版信息

Vet Comp Orthop Traumatol. 2016 Jul 19;29(4):338-43. doi: 10.3415/VCOT-15-11-0183. Epub 2016 Jun 1.

Abstract

OBJECTIVES

To determine if a single low dose of radiation therapy in dogs with osteoarthritis of the elbow joint was associated with a detectable improvement in their lameness and pain as documented by force platform gait analysis.

METHODS

In this cohort longitudinal observational study, five Labrador Retrievers with lameness due to elbow osteoarthritis that was unresponsive to medical treatment were removed from all non-steroidal anti-inflammatory and analgesic medications. A single treatment of radiation therapy delivering 10 Gray was performed on the affected elbow joint(s). Force platform gait analysis was used to assess the ground reaction forces of a limb affected with elbow osteoarthritis both before and after radiation therapy.

RESULTS

Significant differences occurred in the weight-bearing on an affected limb with elbow osteoarthritis after radiation therapy at weeks six and 14. Change due to treatment was particularly apparent in dogs with unilateral elbow osteoarthritis.

CLINICAL SIGNIFICANCE

Administering a single low dose of radiation therapy may have a short-term benefit in dogs with elbow osteoarthritis, which is similar to the evidence supporting the use of radiation therapy in horses with orthopaedic disease.

摘要

目的

通过测力平台步态分析记录,确定对患有肘关节骨关节炎的犬只进行单次低剂量放射治疗是否与可检测到的跛行和疼痛改善相关。

方法

在这项队列纵向观察研究中,将五只因肘关节骨关节炎而跛行且药物治疗无效的拉布拉多猎犬停用所有非甾体抗炎药和镇痛药。对受影响的肘关节进行一次10格雷的放射治疗。在放射治疗前后,使用测力平台步态分析来评估受肘关节骨关节炎影响肢体的地面反作用力。

结果

放射治疗后第6周和第14周,患有肘关节骨关节炎的患侧肢体负重出现显著差异。治疗引起的变化在单侧肘关节骨关节炎的犬只中尤为明显。

临床意义

对患有肘关节骨关节炎的犬只给予单次低剂量放射治疗可能具有短期益处,这与支持对患有骨科疾病的马匹使用放射治疗的证据相似。

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