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亚洲炎症性肠病的治疗:在首尔举行的第二届亚洲克罗恩病和结肠炎组织(AOCC)会议上进行的一项基于网络的多国调查结果

Treatment of inflammatory bowel disease in Asia: the results of a multinational web-based survey in the 2(nd) Asian Organization of Crohn's and Colitis (AOCC) meeting in Seoul.

作者信息

Nakase Hiroshi, Keum Bora, Ye Byoung Duk, Park Soo Jung, Koo Hoon Sup, Eun Chang Soo

机构信息

Department of Gastroenterology and Hepatology, Sapporo Medical University, School of Medicine, Sapporo, Japan.

Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.

出版信息

Intest Res. 2016 Jul;14(3):231-9. doi: 10.5217/ir.2016.14.3.231. Epub 2016 Jun 27.

Abstract

BACKGROUND/AIMS: Inflammatory bowel disease (IBD) management guidelines have been released from Western countries, but no adequate data on the application of these guidelines in Asian countries and no surveys on the treatment of IBD in real practice exist. Since there is a growing need for a customized consensus for IBD treatment in Asian countries, Asian Organization of Crohn's and Colitis performed a multinational survey of medical doctors who treat IBD patients in Asian countries.

METHODS

A questionnaire was developed between August 2013 and November 2013. It was composed of 4 domains: personal information, IBD diagnosis, IBD treatment, and quality of IBD care. Upon completion of the questionnaire, a web-based survey was conducted between 17 March 2014 and 12 May 2014.

RESULTS

In total, 353 medical doctors treating IBD from ten Asian countries responded to the survey. This survey data suggested a difference in available medical treatments (budesonide, tacrolimus) among Asian countries. Therapeutic strategies regarding refractory IBD (acute severe ulcerative colitis [UC] refractory to intravenous steroids and refractory Crohn's disease [CD]) and active UC were coincident, however, induction therapies for mild to moderate inflammatory small bowel CD are different among Asian countries.

CONCLUSIONS

This survey demonstrated that current therapeutic approaches and clinical management of IBD vary among Asian countries. Based on these results and discussions, we hope that optimal management guidelines for Asian IBD patients will be developed.

摘要

背景/目的:西方国家已发布炎症性肠病(IBD)管理指南,但尚无关于这些指南在亚洲国家应用的充分数据,也没有关于IBD实际治疗情况的调查。鉴于亚洲国家对IBD治疗定制化共识的需求日益增长,亚洲克罗恩病和结肠炎组织对亚洲国家治疗IBD患者的医生进行了一项多国调查。

方法

2013年8月至2013年11月期间设计了一份问卷。问卷由4个领域组成:个人信息、IBD诊断、IBD治疗和IBD护理质量。问卷完成后,于2014年3月17日至2014年5月12日进行了基于网络的调查。

结果

来自十个亚洲国家的353名治疗IBD的医生回复了调查。该调查数据表明亚洲国家在可用药物治疗(布地奈德、他克莫司)方面存在差异。然而,关于难治性IBD(对静脉注射类固醇难治的急性重症溃疡性结肠炎[UC]和难治性克罗恩病[CD])和活动期UC的治疗策略是一致的,亚洲国家对轻度至中度炎症性小肠CD的诱导治疗有所不同。

结论

本次调查表明,亚洲国家IBD的当前治疗方法和临床管理存在差异。基于这些结果和讨论,我们希望能制定出针对亚洲IBD患者的最佳管理指南。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b469/4945527/7c809777c355/ir-14-231-g002.jpg

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