Puckett Yana, Ta Anh
Surgery, Texas Tech University Health Sciences Center.
School of Medicine, Saint Louis University.
Cureus. 2016 May 27;8(5):e624. doi: 10.7759/cureus.624.
Our objective was to determine the risk factors for inpatient mortality of pediatric patients diagnosed with lymphoma through the utilization of a large national pediatric database.
This cross-sectional study uses data from the Healthcare Cost and Utilization Project Kids' Inpatient Database (HCUP KID) for the year of 2012 to estimate the risk factors for inpatient mortality for pediatric patients diagnosed with lymphoma. All patients diagnosed with lymphoma between the ages of one and 18 years were included. Chi-square test was used to analyze categorical variables. Independent t-test was used to analyze continuous variables.
A total of 2,908 study subjects with lymphoma were analyzed. Of those, 56.1% were male and the average age was three years old. Total inpatient mortality was 1.2% or 34 patients. We found that patients with four or more chronic conditions were much more likely to die while hospitalized (p < 0.0001). In addition, we also saw that patients with median household incomes below $47,999 dollars (p = 0.05) having a need for a major procedure (p = 0.008) were associated with inpatient mortality. Congestive heart failure, renal failure, coagulopathy, metastatic disease, and electrolyte abnormalities were all found to be associated with inpatient mortality.
Pediatric lymphoma mortality in children is not only influenced by their medical condition but also by their socioeconomic condition as well.
我们的目标是通过利用一个大型国家儿科数据库，确定被诊断为淋巴瘤的儿科患者住院死亡率的风险因素。
这项横断面研究使用了2012年医疗成本和利用项目儿童住院数据库（HCUP KID）的数据，以估计被诊断为淋巴瘤的儿科患者住院死亡率的风险因素。纳入所有年龄在1至18岁之间被诊断为淋巴瘤的患者。采用卡方检验分析分类变量。采用独立t检验分析连续变量。
共分析了2908名患有淋巴瘤的研究对象。其中，56.1%为男性，平均年龄为3岁。总住院死亡率为1.2%，即34名患者。我们发现，患有四种或更多慢性病的患者在住院期间死亡的可能性要大得多（p<0.0001）。此外，我们还发现，家庭收入中位数低于47999美元的患者（p=0.05）以及需要进行大手术的患者（p=0.008）与住院死亡率相关。充血性心力衰竭、肾衰竭、凝血障碍、转移性疾病和电解质异常均与住院死亡率相关。
儿童淋巴瘤死亡率不仅受其病情影响，还受其社会经济状况影响。
