Bouin Alexis, Nguyen Yohan, Wehbe Michel, Renois Fanny, Fornes Paul, Bani-Sadr Firouze, Metz Damien, Andreoletti Laurent
Emerg Infect Dis. 2016 Aug;22(8):1488-90. doi: 10.3201/eid2208.160186.
We performed deep sequencing analysis of the enterovirus 5' noncoding region in cardiac biopsies from a patient with dilated cardiomyopathy. Results displayed a mix of deleted and full-length coxsackievirus B3, characterized by a low viral RNA load (8.10(2) copies/μg of nucleic acids) and a low viral RNA positive-sense to RNA negative-sense ratio of 4.8.
我们对一名扩张型心肌病患者心脏活检组织中的肠道病毒5'非编码区进行了深度测序分析。结果显示，柯萨奇病毒B3存在缺失型和全长型混合的情况，其特征为病毒RNA载量较低（8.10(2)拷贝/μg核酸），病毒RNA正链与负链的比例较低，为4.8。
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