Kuriakose Kevin, Klair Jagpal Singh, Johnsrud Andrew, Meena Nikhil K
J Ark Med Soc. 2016 Jun;112(14):282-3.
We report a case of Acute Eosinophilic Pneumonia (AEP) in a 29-year-old white woman with recent use of a'flea bomb' (containing pyrethroids) at home while remaining indoors, about 48 hours prior to presentation, and recent change in smoking habit (restarted 2 weeks prior after quitting for 10 years). She presented with two days of worsening fever, shortness of breath, productive cough, developed hypoxemic respiratory failure and ARDS. She required a PEEP of 20 and 100% FiO2 to maintain oxygenation. Bronchoalveolar lavage showed 36% Eosinophils. She was given IV steroids with dramatic clinical and radiological improvement. To the best of our knowledge, this is the second report associating AEP with pyrethroid exposure.
我们报告一例29岁白人女性的急性嗜酸性粒细胞性肺炎（AEP）。该患者在就诊前约48小时，于室内使用了一枚“灭蚤弹”（含拟除虫菊酯），且近期吸烟习惯有改变（戒烟10年后于2周前重新开始吸烟）。她出现了两天的发热加重、呼吸急促、咳痰，发展为低氧性呼吸衰竭和急性呼吸窘迫综合征（ARDS）。她需要20cmH₂O的呼气末正压通气（PEEP）和100%的吸入氧浓度（FiO₂）来维持氧合。支气管肺泡灌洗显示嗜酸性粒细胞占36%。她接受了静脉注射类固醇治疗，临床和影像学表现均有显著改善。据我们所知，这是第二例将AEP与拟除虫菊酯暴露相关联的报告。
