School of Psychological Sciences, Tel-Aviv University, Tel-Aviv, Israel.
The Emotion and Development Branch, Intramural Research Program, National Institute of Mental Health, Bethesda, MD, USA.
J Child Psychol Psychiatry. 2016 Nov;57(11):1317-1325. doi: 10.1111/jcpp.12599. Epub 2016 Jul 20.
Attention bias modification treatment (ABMT) targets threat-related attention biases in anxiety disorders. Most clinical trials of ABMT have focused on adults or small samples of youth. The current randomized controlled trial (RCT) examines ABMT efficacy in youth with social anxiety disorder (SAD) and tests possible moderators of treatment outcomes.
Sixty-seven youth with SAD were randomly assigned to ABMT or attention control training (ACT) conditions. Anxiety severity was measured at baseline, posttreatment, and 3-month follow-up. ClinicalTrials.gov name and identifier: Attention bias modification treatment for children with social anxiety, NCT01397032; http://www.clinicaltrials.gov.
Both ABMT and ACT induced significant reductions in clinician and self-rated social anxiety (ps < .001). An additional reduction was observed at the 3-month follow-up in clinician-rated anxiety symptoms (p = .03). Moderation effects were nonsignificant for the clinician-rated anxiety outcome, but age moderated self-reported anxiety. Older but not younger children, showed significant reduction in anxiety following ABMT relative to ACT (p < .001). Individual differences in attention control also moderated ABMT's effect on self-reported anxiety (p = .05). Children rated by their parents as lower on attention control benefited more from ABMT than those rated higher on attention control. Baseline attention bias did not moderate anxiety (p = .17).
Despite significant reductions in social anxiety, no specific evidence for ABMT was found relative to a control condition. Age and attention control moderated ABMT effects on self-reported SAD symptoms, with clinical effects for older relative to younger children and for those with lower attention control. These results highlight the need to consider developmental influences in the implementation of ABMT protocols.
注意偏向修正治疗(ABMT)针对焦虑障碍中的与威胁相关的注意偏向。大多数 ABMT 的临床试验都集中在成年人或青少年的小样本上。目前的随机对照试验(RCT)检验了 ABMT 在社交焦虑障碍(SAD)青少年中的疗效,并测试了治疗结果的可能调节因素。
67 名患有 SAD 的青少年被随机分配到 ABMT 或注意控制训练(ACT)条件下。在基线、治疗后和 3 个月随访时测量焦虑严重程度。ClinicalTrials.gov 名称和标识符:针对社交焦虑儿童的注意偏向修正治疗,NCT01397032;http://www.clinicaltrials.gov。
ABMT 和 ACT 均显著降低了临床医生和自我报告的社交焦虑(p <.001)。在临床医生评定的焦虑症状中,还观察到 3 个月随访时的额外降低(p =.03)。对于临床评定的焦虑结果,调节作用不显著,但年龄调节了自我报告的焦虑。与 ACT 相比,ABMT 后年龄较大但年龄较小的儿童焦虑显著降低(p <.001)。注意控制的个体差异也调节了 ABMT 对自我报告焦虑的影响(p =.05)。与注意力控制较高的儿童相比,父母评定注意力控制较低的儿童从 ABMT 中受益更多。注意偏向在基线时不能调节焦虑(p =.17)。
尽管社交焦虑显著降低,但相对于对照条件,ABMT 没有发现特定的证据。年龄和注意控制调节了 ABMT 对自我报告的 SAD 症状的影响,对于年龄较大的儿童相对于年龄较小的儿童以及注意力控制较低的儿童,具有临床效果。这些结果强调了在实施 ABMT 方案时需要考虑发展影响的必要性。