AlObaidy Mamdoh, Ramalho Miguel, Velloni Fernanda, Matos António P, Herman Kevin, Semelka Richard C
Department of Radiology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Department of Radiology, University of North Carolina at Chapel Hill, CB 7510-2001 Old Clinic Bldg., Chapel Hill, NC, 27599-7510, USA.
Eur Radiol. 2017 Apr;27(4):1596-1604. doi: 10.1007/s00330-016-4494-0. Epub 2016 Jul 19.
To quantitatively compare the extent of enhancement of abdominal structures on MRI in an intraindividual fashion at 1.5 and 3 T.
HIPAA-compliant, retrospective, longitudinal, intraindividual, crossover study, with waived informed consent, of consecutive individuals scanned at both 1.5 and 3 T closed-bore magnets using gadobenate dimeglumine during different phases of enhancement at tightly controlled arterial phase timing. Quantitative ROI measurements and qualitative sub-phase arterial phase assignments were independently performed by two radiologists. Qualitative discrepancies were resolved by a senior radiologist.
Final population included 60 patients [41 female and 19 male; age, 49.35 ± 18.31 years (range 16-81); weight, 78.88 ± 20.3 kg (range 44.5-136)]. Similar enhancement peak patterns were noted at both field strengths. Interobserver agreement of quantitative evaluations was substantial. Significantly higher amplitudes of enhancement peaks were noted for all abdominal solid organs during all phases at 3 T, except for the pancreas (p = 0.17-0.30). Significantly higher amplitudes of enhancement peaks of the abdominal aorta at 1.5 T were noted.
Similar peak patterns of enhancement for abdominal structures were observed at 1.5 and 3 T, with solid abdominal organs showing a higher percentage enhancement at 3 T, while unexpectedly higher aortic higher percentage enhancement was observed at 1.5 T.
• Similar enhancement peak patterns at both field strengths for studied abdominal structures. • Significantly higher percentage enhancement of most abdominal organs at 3 T. • Non-statistically significant trend of higher pancreatic percentage enhancement at 3 T. • Significantly lower abdominal aortic percentage enhancement at 3 T.
以个体内比较的方式,定量比较腹部结构在1.5T和3T磁共振成像(MRI)上的强化程度。
本研究为符合健康保险流通与责任法案(HIPAA)要求的回顾性、纵向、个体内交叉研究,在获得豁免知情同意的情况下,对连续的个体在1.5T和3T的封闭孔磁体上进行扫描,使用钆贝葡胺,并在严格控制的动脉期时间的不同强化阶段进行扫描。两名放射科医生独立进行定量感兴趣区(ROI)测量和定性的亚期动脉期赋值。定性差异由一名资深放射科医生解决。
最终纳入60例患者[41例女性和19例男性;年龄,49.35±18.31岁(范围16 - 81岁);体重,78.88±20.3kg(范围44.5 - 136kg)]。在两个场强下均观察到相似的强化峰值模式。定量评估的观察者间一致性较高。在3T时,除胰腺外(p = 0.17 - 0.30),所有腹部实体器官在各阶段的强化峰值幅度均显著更高。在1.5T时观察到腹主动脉强化峰值幅度显著更高。
在1.5T和3T时观察到腹部结构的强化峰值模式相似,腹部实体器官在3T时强化百分比更高,而意外的是,腹主动脉在1.5T时强化百分比更高。
• 研究的腹部结构在两个场强下强化峰值模式相似。• 3T时大多数腹部器官强化百分比显著更高。• 3T时胰腺强化百分比有更高的趋势,但无统计学意义。• 3T时腹主动脉强化百分比显著更低。