Segev Gilad, Meltzer Hagar, Shipov Anna
Koret School of Veterinary Medicine, The Hebrew University of Jerusalem, Hertzel Street, Rehovot 76100, Israel.
Koret School of Veterinary Medicine, The Hebrew University of Jerusalem, Hertzel Street, Rehovot 76100, Israel.
Vet Clin North Am Small Anim Pract. 2016 Nov;46(6):1151-62. doi: 10.1016/j.cvsm.2016.06.006. Epub 2016 Jul 16.
Secondary renal hyperparathyroidism is an inevitable consequence of chronic kidney disease. In human patients, the disease is associated with decreased bone quality and increased fracture risk. Recent evidence suggests that bone quality is also decreased in companion animals, more pronouncedly in cats compared with dogs, likely because of a longer disease course. The clinical significance of these findings is yet to be determined. However, clinicians should keep in mind that animals with chronic kidney disease have decreased bone quality and increased fracture risk.
继发性肾性甲状旁腺功能亢进是慢性肾脏病不可避免的后果。在人类患者中,该疾病与骨质下降和骨折风险增加有关。最近的证据表明,伴侣动物的骨质也会下降,与犬相比,猫的骨质下降更为明显,这可能是由于病程更长。这些发现的临床意义尚待确定。然而,临床医生应牢记,患有慢性肾脏病的动物骨质下降且骨折风险增加。