State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, PR China.
State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, PR China.
Curr Opin Insect Sci. 2016 Jun;15:139-43. doi: 10.1016/j.cois.2016.04.004. Epub 2016 May 17.
Many lines of insect-resistant genetically modified (IRGM) corn and rice containing Bacillus thuringiensis (Bt) insecticidal genes have been developed and undergone different environmental biosafety assessments stages in China, showing robust application prospects. The potential of targeted pests to develop resistance to Bt crops is widespread, which threatens the sustainable utility of IRGM corn and rice. In this study, the potential risks of target pest complexes developing resistance to IRGM corn and rice are evaluated. Theoretical and empirical studies implementing precautionary insect resistance management (IRM) strategies to delay resistance evolution are summarized and challenges to IRM are discussed. Additionally, solutions facing these challenges are proposed. Finally, directions for future studies in developing IRGM corn and rice and IRM plans are discussed.
许多含有苏云金芽孢杆菌（Bt）杀虫基因的抗虫转基因玉米和水稻已经被开发出来，并在中国经历了不同的环境生物安全评估阶段，显示出了强大的应用前景。目标害虫对Bt 作物产生抗性的潜力是广泛存在的，这威胁到了抗虫转基因玉米和水稻的可持续利用。在本研究中，评估了目标害虫复合体对抗虫转基因玉米和水稻产生抗性的潜在风险。总结了实施预防性昆虫抗性管理（IRM）策略以延迟抗性进化的理论和实证研究，并讨论了 IRM 所面临的挑战。此外，还提出了应对这些挑战的解决方案。最后，讨论了开发抗虫转基因玉米和水稻和 IRM 计划的未来研究方向。
