Kluin Jolanda, Koolbergen David R, Sojak Vladimir, Hazekamp Mark G
Department of Cardiothoracic Surgery, Leiden University Center, Leiden, Netherlands Department of Cardiothoracic Surgery, Academic Medical Center, Amsterdam, Netherlands.
Department of Cardiothoracic Surgery, Leiden University Center, Leiden, Netherlands Department of Cardiothoracic Surgery, Academic Medical Center, Amsterdam, Netherlands
Eur J Cardiothorac Surg. 2016 Sep;50(3):476-81. doi: 10.1093/ejcts/ezw096. Epub 2016 Jul 19.
In children, words of caution have been raised about valve-sparing procedures especially regarding the valve-remodelling technique. This study reviewed our experience with the valve-sparing reimplantation technique in children.
All consecutive paediatric (<18 years) patients who underwent valve-sparing root replacement in our centre in the past 12.5 years were retrospectively analysed.
Nineteen patients (median age 13.2 years, 10 months to 17.9 years) underwent valve-sparing root replacement using the reimplantation technique. Seventeen had connective tissue disease. An adult-sized vascular prosthesis could be implanted in all cases. Additional cusp repair was required in 3 patients. Follow-up was 4.4 ± 3.8 years. There was no perioperative mortality and one late death. Of the 3 patients that needed cusp repair, 1 developed Grade 3 aortic valve regurgitation (AR) and required aortic valve replacement and 2 had Grade 1 AR. Ninety-four percent of the other patients had Grade 0 AR at latest follow-up, 1 patient (6%) had Grade 1 AR.
Our data show that valve-sparing root surgery using the reimplantation technique can be performed safely in children. Mid-term follow-up yields stable and favourable results. When leaflet reconstruction is necessary on top of the reimplantation procedure, rate of recurrent AR seems to be higher.
在儿童中,对于保留瓣膜手术尤其是瓣膜重塑技术已提出了一些警示。本研究回顾了我们在儿童保留瓣膜再植入技术方面的经验。
对过去12.5年内在我们中心接受保留瓣膜根部置换术的所有连续儿科(<18岁)患者进行回顾性分析。
19例患者(中位年龄13.2岁,10个月至17.9岁)采用再植入技术接受了保留瓣膜根部置换术。17例患有结缔组织病。所有病例均能植入成人尺寸的血管假体。3例患者需要额外的瓣叶修复。随访时间为4.4±3.8年。围手术期无死亡病例,1例晚期死亡。在需要瓣叶修复的3例患者中,1例出现3级主动脉瓣反流(AR)并需要进行主动脉瓣置换,2例为1级AR。在最新随访时,其他患者中有94%为0级AR,1例患者(6%)为1级AR。
我们的数据表明,采用再植入技术的保留瓣膜根部手术在儿童中可以安全进行。中期随访结果稳定且良好。在再植入手术基础上需要进行瓣叶重建时,复发性AR的发生率似乎更高。