Hopkins A, Zylstra S, Hreshchyshyn M M, Anbar M
Department of Biophysical Sciences, School of Medicine and Biomedical Sciences, SUNY, Buffalo 14214.
Clin Nucl Med. 1989 Jun;14(6):410-4. doi: 10.1097/00003072-198906000-00003.
Dual photon absorptiometry (DPA) is an extensively used technique for measuring the density of the lumbar spine. The presence of vertebral and extra-vertebral pathologies can lead to increased scatter of data and artifactual bias when constructing diagnostic reference value curves. The bone density of patients with such abnormalities cannot be compared with those of normals because it will appear artificially high. Furthermore, little effort has been made to identify and evaluate spinal abnormalities using the pictograms produced in this method. We have analyzed 60 DPA scans for morphologic changes, using x-rays for comparison, and have found practically complete concurrence between these two radiologic methods on features, though only the former is capable of accurately quantifying bone density. Examples of DPA presentation of anatomical morphology are shown to aid the user in interpreting DPA findings.
双能光子吸收测定法(DPA)是一种广泛用于测量腰椎骨密度的技术。当构建诊断参考值曲线时,椎体和椎体外病变的存在会导致数据散射增加和人为偏差。患有此类异常的患者的骨密度无法与正常人的骨密度进行比较,因为其数值会显得人为偏高。此外,利用这种方法生成的象形图来识别和评估脊柱异常的工作做得很少。我们分析了60例DPA扫描图像的形态学变化,并使用X射线进行比较,发现这两种放射学方法在特征方面几乎完全一致,不过只有前者能够准确量化骨密度。文中展示了DPA呈现解剖形态的示例,以帮助使用者解读DPA检查结果。