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模仿腰椎神经鞘瘤的弥漫性大B细胞淋巴瘤

Diffuse Large B-Cell Lymphoma Mimicking Schwannoma of Lumbar Spine.

作者信息

Kim Seung-Kook, Lee Sun-Ho, Kim Eun-Sang, Eoh Whan

机构信息

Department of Neurosurgery, Spine Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

出版信息

Korean J Spine. 2016 Jun;13(2):71-3. doi: 10.14245/kjs.2016.13.2.71. Epub 2016 Jun 30.

Abstract

A rare case of solitary diffuse large B-cell lymphoma arising from the lumbar spinal nerve root is reported. A 37-year-old man presented with a 3-month history of progressive numbness and paraparesis in both legs. The initial diagnosis was benign primary intradural extramedullary tumor including schwannoma and meningioma. Histopathological examination revealed diffuse large B-cell lymphoma. While a well-defined T1 isointense mass is common in primary spinal schwannoma, the present case was atypical and had a yellowish neural component. The pathogenesis and radiological findings of spinal diffuse large B-cell lymphoma are discussed and related literature is reviewed.

摘要

报告了一例罕见的起源于腰段脊神经根的孤立性弥漫性大B细胞淋巴瘤。一名37岁男性,有3个月双下肢进行性麻木和轻瘫病史。最初诊断为良性原发性硬脊膜内髓外肿瘤,包括神经鞘瘤和脑膜瘤。组织病理学检查显示为弥漫性大B细胞淋巴瘤。虽然在原发性脊髓神经鞘瘤中边界清晰的T1等信号肿块很常见,但本例不典型,有淡黄色神经成分。讨论了脊髓弥漫性大B细胞淋巴瘤的发病机制和影像学表现,并复习了相关文献。

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