Mahadevappa Manjappa, Hegde Madhav, Math Ravi
Assistant Professor, Department of Cardiology, JSS Medical College , Mysore, Karnataka, India .
Associate Professor, Department of Radiology, Dr. B.R. Ambedkar Medical College , Bengaluru, Karnataka, India .
J Clin Diagn Res. 2016 May;10(5):TC10-3. doi: 10.7860/JCDR/2016/18096.7849. Epub 2016 May 1.
The normative data of coronary artery size among Indians are sparse. It is often essential to know the coronary dimensions especially during interventions such as stenting to choose the appropriate size of the stent and to decide the very need for stenting. In current practice it is the luminal angiography which is most widely employed to assess the coronary artery size. However, luminal angiography is not very accurate in estimating the epicardial coronary artery size as it does not take into account the mural thickness of the arterial wall. Hence it is prudent to assess coronary artery size by other methods such as Computed Tomography (CT) coronary angiography, quantitative coronary angiogram, Magnetic Resonanace (MR) angiogram, etc. In this study we chose computed tomography as it demonstrates mural thickness along with lumen of the vessels and hence measures the diameter more accurately.
To establish normative data for diameters of the proximal coronary artery segments during life by using MDCT in a cohort of individuals without any structural heart disease.
Between October 2012 and April 2013, 168 consecutive patients who did not have any structural heart disease underwent CT coronary angiography for evaluation of Coronary Artery Disease (CAD) with atypical symptoms with low pretest probability. Patients who were found to have no coronary artery disease on CT-CAG were recruited in this study. The baseline clinical status and demographic data were obtained from the hospital records.
In our study we found that the mean indexed diameter to BSA among females for LMCA 2.32±0.12mm, LAD 1.95±0.15mm, LCX 1.73±0.20mm and RCA 1.84±0.22mm. For males the values were LMCA 2.33±0.13mm, LAD 1.94±0.16mm, LCX 1.74±0.21mm, and RCA 1.79±0.20mm. These values are comparable to other studies.
We attempted to establish normative data for normal proximal coronary artery dimensions among South Indian population. Coronary artery dimensions in Indians (in-dexed to BSA) for proximal major epicardial coronary arteries are similar to that reported in the West.
印度人群冠状动脉大小的规范数据稀少。了解冠状动脉尺寸通常至关重要,尤其是在诸如支架置入等干预过程中,以便选择合适尺寸的支架并确定是否确实需要进行支架置入。在当前实践中,最广泛用于评估冠状动脉大小的是腔内血管造影。然而,腔内血管造影在估计心外膜冠状动脉大小时并不十分准确,因为它没有考虑动脉壁的壁厚度。因此,通过其他方法如计算机断层扫描(CT)冠状动脉造影、定量冠状动脉造影、磁共振(MR)血管造影等来评估冠状动脉大小是明智的。在本研究中,我们选择了计算机断层扫描,因为它能显示血管壁厚度以及管腔,从而更准确地测量直径。
通过使用多层螺旋CT(MDCT),为一组无任何结构性心脏病的个体建立生前近端冠状动脉节段直径的规范数据。
在2012年10月至2013年4月期间,168例无任何结构性心脏病的连续患者因非典型症状且预检概率低而接受CT冠状动脉造影以评估冠状动脉疾病(CAD)。在CT冠状动脉造影(CT-CAG)中未发现冠状动脉疾病的患者被纳入本研究。基线临床状况和人口统计学数据从医院记录中获取。
在我们的研究中,我们发现女性左主干(LMCA)相对于体表面积(BSA)的平均指数直径为2.32±0.12mm,左前降支(LAD)为1.95±0.15mm,左旋支(LCX)为1.73±0.20mm,右冠状动脉(RCA)为1.84±0.22mm。男性的数值分别为LMCA 2.33±0.13mm,LAD 1.94±0.16mm,LCX 1.74±0.21mm,RCA 1.79±0.20mm。这些数值与其他研究结果相当。
我们试图为南印度人群正常近端冠状动脉尺寸建立规范数据。印度人近端主要心外膜冠状动脉(相对于BSA)的尺寸与西方报道的相似。