Department of Anatomy, Yenepoya Medical College, Yenepoya (Deemed to be) University, Deralakatte, Mangalore, 575018, Karnataka, India.
Department of Cardio Vascular Sciences, Sahakarana Hrudayalaya, Government Medical College, Pariyaram, Kannur, Kerala, 670503, India.
Indian Heart J. 2021 May-Jun;73(3):347-352. doi: 10.1016/j.ihj.2021.04.001. Epub 2021 Apr 15.
Coronary artery disease (CAD) is the most common cause of morbidity and mortality especially in the developing countries. Coronary artery measurements (CAM) are the most important factor affecting the procedure and outcome of coronary angioplasty (PCI) as well as coronary by-pass operations (CABG). In this study, we aimed to establish a database for the normal CAM as well as for gender difference among the Indian population using quantitative coronary angiography (QCA) with an objective of assessing normal coronary vessel morphology of patients with normal coronaries.
Four thousand angiograms from patients of Indian origin were studied prospectively after procuring the sanction for the same from the ethical committee of the pre-selected hospitals of four states in India. Informed consents were obtained. Post CABG, post PCI patients and patient being diabetic for ≥5 years were also excluded from the study.
Ten segments from right and left coronary arteries were taken for diameter measurements. These coronary diameters were indexed to body surface area (BSA) (mean diameter mm/m BSA). Among, 4000 patients, 933(23.3%) [M:F-521:412] had normal coronaries and 3067 (76.7%) were diseased.
The dimensions of the coronary artery segments of Indians were smaller (in BSA indexed and non-indexed data), compared to studies from other continents which can be due to their smaller BSA.
冠心病（CAD）是发病率和死亡率最高的疾病，尤其在发展中国家。冠状动脉测量（CAM）是影响经皮冠状动脉介入治疗（PCI）和冠状动脉旁路移植术（CABG）过程和结果的最重要因素。在这项研究中，我们旨在使用定量冠状动脉造影术（QCA）建立一个数据库，用于记录印度人群的正常 CAM 以及性别差异，目的是评估正常冠状动脉患者的正常冠状动脉血管形态。
前瞻性地研究了来自印度裔患者的 4000 份血管造影图，在获得印度四个州选定医院伦理委员会的批准后进行研究。获得了知情同意。也排除了 CABG 后、PCI 后以及糖尿病≥5 年的患者。
从左右冠状动脉中取 10 个节段进行直径测量。这些冠状动脉直径与体表面积（BSA）（平均直径 mm/m BSA）进行了指数化。在 4000 例患者中，933 例（23.3%）[M:F-521:412]有正常的冠状动脉，3067 例（76.7%）有病变。
与来自其他大陆的研究相比，印度人的冠状动脉节段的尺寸较小（在 BSA 指数和非指数数据中），这可能是由于他们的 BSA 较小。
